Compile Data Set for Download or QSAR
Report error Found 587 of affinity data for UniProtKB/TrEMBL: P07374
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50532145BDBM50532145(CHEMBL1549559)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50223161BDBM50223161(1-cyclohexyl-1-isopropyl-3,3-dimethylselenourea | ...)
Affinity DataKi:  25nMAssay Description:Inhibition of jack bean ureaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253257BDBM50253257(CHEMBL4100084)
Affinity DataIC50: 50nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178021BDBM178021((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 58nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253269BDBM50253269(CHEMBL4092986)
Affinity DataIC50: 60nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178020BDBM178020((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 64nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178016BDBM178016((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 72nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 152597BDBM152597(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-nitrophenyl...)
Affinity DataIC50: 77nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 µL of enzyme (5 U/mL) and 10 µL of each test compound in the series (3a-3s) in 40 µL b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178019BDBM178019((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 81nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178022BDBM178022((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 83nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178017BDBM178017((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 83nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178014BDBM178014((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 87nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178015BDBM178015((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 87nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 152587BDBM152587(2-(1-(Benzofuran-2-yl)ethylidene)-N-phenylhydrazin...)
Affinity DataIC50: 89nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 µL of enzyme (5 U/mL) and 10 µL of each test compound in the series (3a-3s) in 40 µL b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356190BDBM50356190(CHEMBL193474)
Affinity DataKi:  90nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50223158BDBM50223158((S)-1,1-dimethyl-3-(1-(naphthalen-1-yl)ethyl)selen...)
Affinity DataKi:  94nMAssay Description:Inhibition of jack bean ureaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 178013BDBM178013((Z)-N-(3-(4-aminosulfonylphenyl)-4-methylthiazol-2...)
Affinity DataIC50: 96nMpH: 8.2Assay Description:The urease inhibitory activity of synthesized sulfonamides (3a-j) was determined by measuring the amount of ammonia produced by the indophenols metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356190BDBM50356190(CHEMBL193474)
Affinity DataIC50: 102nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 152600BDBM152600(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-methoxyphen...)
Affinity DataIC50: 102nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 µL of enzyme (5 U/mL) and 10 µL of each test compound in the series (3a-3s) in 40 µL b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123230BDBM50123230(CHEMBL3622691)
Affinity DataIC50: 120nMAssay Description:Inhibition of jack beans urease assessed as hydrolysis of urea into ammonia preincubated for 10 mins followed by urea addition measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356195BDBM50356195(CHEMBL241902)
Affinity DataKi:  122nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50223159BDBM50223159(3-dodecyl-1,1-dimethylthiourea | CHEMBL251521)
Affinity DataKi:  124nMAssay Description:Inhibition of jack bean ureaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 53627BDBM53627([[(E)-(5-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene...)
Affinity DataKi:  127nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356195BDBM50356195(CHEMBL241902)
Affinity DataIC50: 127nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356192BDBM50356192(CHEMBL241894)
Affinity DataKi:  127nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 110170BDBM110170(Ethyl 4-[3-(3,4-dimethoxybenzoyl)thioureido]benzoa...)
Affinity DataIC50: 130nMpH: 8.2 T: 2°CAssay Description:The assay mixture contained 40 µL of buffer (0.01 M LiCl2, 1 mM EDTA, 0.01M K2HPO4, pH 8.2) containing 100 mM urea, 10 µL of enzyme (5U/mL)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356201BDBM50356201(CHEMBL1910224)
Affinity DataKi:  134nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50223157BDBM50223157(3-(4-bromobenzyl)-1,1-dimethylselenourea | CHEMBL3...)
Affinity DataKi:  135nMAssay Description:Inhibition of jack bean ureaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452584BDBM50452584(CHEMBL4208211)
Affinity DataIC50: 140nMAssay Description:Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253270BDBM50253270(CHEMBL4071196)
Affinity DataIC50: 140nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253275BDBM50253275(CHEMBL4092021)
Affinity DataIC50: 150nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123347BDBM50123347(CHEMBL3622680)
Affinity DataIC50: 150nMAssay Description:Inhibition of jack beans urease assessed as hydrolysis of urea into ammonia preincubated for 10 mins followed by urea addition measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356197BDBM50356197(CHEMBL1910221)
Affinity DataKi:  152nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123229BDBM50123229(CHEMBL3622693)
Affinity DataIC50: 160nMAssay Description:Inhibition of jack beans urease assessed as hydrolysis of urea into ammonia preincubated for 10 mins followed by urea addition measured after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356186BDBM50356186(CHEMBL239452)
Affinity DataKi:  170nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253254BDBM50253254(CHEMBL4070510)
Affinity DataIC50: 170nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253258BDBM50253258(CHEMBL4103174)
Affinity DataIC50: 170nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 152591BDBM152591(2-(1-(Benzofuran-2-yl)ethylidene)-N-(4-fluoropheny...)
Affinity DataIC50: 177nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 µL of enzyme (5 U/mL) and 10 µL of each test compound in the series (3a-3s) in 40 µL b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356192BDBM50356192(CHEMBL241894)
Affinity DataIC50: 177nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 152598BDBM152598(2-(1-(Benzofuran-2-yl)ethylidene)-N-(4-nitrophenyl...)
Affinity DataIC50: 181nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 µL of enzyme (5 U/mL) and 10 µL of each test compound in the series (3a-3s) in 40 µL b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356198BDBM50356198(CHEMBL1910222)
Affinity DataKi:  191nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50488912BDBM50488912(CHEMBL2298033)
Affinity DataKi:  200nMAssay Description:Inhibition of Canavalia ensiformis (jack bean) urease assessed as release of ammonia after 30 min by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 110169BDBM110169(Ethyl 4-[3-(4-methoxybenzoyl)thioureido]benzoate (...)
Affinity DataIC50: 210nMpH: 8.2 T: 2°CAssay Description:The assay mixture contained 40 µL of buffer (0.01 M LiCl2, 1 mM EDTA, 0.01M K2HPO4, pH 8.2) containing 100 mM urea, 10 µL of enzyme (5U/mL)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356186BDBM50356186(CHEMBL239452)
Affinity DataIC50: 215nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 53627BDBM53627([[(E)-(5-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene...)
Affinity DataIC50: 220nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253271BDBM50253271(CHEMBL4065321)
Affinity DataIC50: 220nMAssay Description:Inhibition of jack bean urease using urea as substrate pretreated for 15 mins followed by substrate addition by phenol red based spectrophotometric m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2019
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356201BDBM50356201(CHEMBL1910224)
Affinity DataIC50: 233nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50223160BDBM50223160(3-(4-bromophenyl)-1,1-dimethylthiourea | CHEMBL249...)
Affinity DataKi:  255nMAssay Description:Inhibition of jack bean ureaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 110165BDBM110165(Ethyl 4-[3-(3-chlorobenzoyl)thioureido]benzoate (1...)
Affinity DataIC50: 260nMpH: 8.2 T: 2°CAssay Description:The assay mixture contained 40 µL of buffer (0.01 M LiCl2, 1 mM EDTA, 0.01M K2HPO4, pH 8.2) containing 100 mM urea, 10 µL of enzyme (5U/mL)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetUrease(Jack bean)
University of Karachi

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356197BDBM50356197(CHEMBL1910221)
Affinity DataIC50: 263nMAssay Description:Inhibition of jack bean urease assessed as ammonia production after 30 mins by indophenol methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
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