Compile Data Set for Download or QSAR
Report error Found 1131 for UniProtKB: P31421
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM212860(US9278960, 2-7 | US9663506, Example 2-7)
Affinity DataIC50: 8.90nMAssay Description:Negative allosteric modulation of rat mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  9.80nMAssay Description:Agonist activity at mGlu2/3 receptor in Sprague-Dawley rat forebrain assessed as inhibition of spontaneous Ca2+ oscillations in cortical neurons afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50467057(CHEMBL4295230)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modulation of recombinant rat Gi-coupled mGluR2 expressed in HEK293 Flp-in-T-REx cells with Galpha16 assessed as increase in glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50576816(CHEMBL4846872)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulator activity at rat mGlu2 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393857(US9969726, Example 149 | US10597367, Example 149)
Affinity DataEC50:  20nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393882(US9969726, Example 179 | US10597367, Example 179)
Affinity DataEC50:  20nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393906(US9969726, Example 203 | US10597367, Example 203)
Affinity DataEC50:  20nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393906(US9969726, Example 203 | US10597367, Example 203)
Affinity DataEC50:  20nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50467052(CHEMBL4279401)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulation of recombinant rat Gi-coupled mGluR2 expressed in HEK293 Flp-in-T-REx cells with Galpha16 assessed as increase in glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393882(US9969726, Example 179 | US10597367, Example 179)
Affinity DataEC50:  20nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393857(US9969726, Example 149 | US10597367, Example 149)
Affinity DataEC50:  20nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50576836(CHEMBL4853369)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulator activity at rat mGlu2 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50576811(CHEMBL4863303)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulator activity at rat mGlu2 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM430158(4-(2-fluoro-4-methoxyphenyl)-5-((2-methylpyridin-4...)
Affinity DataIC50: 29nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50467054(CHEMBL4288731)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of recombinant rat Gi-coupled mGluR2 expressed in HEK293 Flp-in-T-REx cells with Galpha16 assessed as increase in glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393886(US9969726, Example 183 | US10597367, Example 183)
Affinity DataEC50:  30nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393886(US9969726, Example 183 | US10597367, Example 183)
Affinity DataEC50:  30nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50056272((2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxy...)
Affinity DataEC50:  35nMAssay Description:Tested for the agonistic activity against Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM430113(4-(2-fluoro-4-methoxyphenyl)-5-(pyridin-3-ylmethox...)
Affinity DataIC50: 39nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393848(US9969726, Example 136 | US10597367, Example 136)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393885(US9969726, Example 182 | US10597367, Example 182)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393885(US9969726, Example 182 | US10597367, Example 182)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393797(US9969726, Example 86 | US10597367, Example 86)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393797(US9969726, Example 86 | US10597367, Example 86)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393885(US9969726, Example 182 | US10597367, Example 182)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393848(US9969726, Example 136 | US10597367, Example 136)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393885(US9969726, Example 182 | US10597367, Example 182)
Affinity DataEC50:  40nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393749(US9969726, Example 39 | US10597367, Example 39)
Affinity DataEC50:  50nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393748(US9969726, Example 38 | US10597367, Example 38)
Affinity DataEC50:  50nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393748(US9969726, Example 38 | US10597367, Example 38)
Affinity DataEC50:  50nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50576842(CHEMBL4866466)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulator activity at rat mGlu2 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393831(US9969726, Example 119 | US10597367, Example 119)
Affinity DataEC50:  50nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393831(US9969726, Example 119 | US10597367, Example 119)
Affinity DataEC50:  50nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393749(US9969726, Example 39 | US10597367, Example 39)
Affinity DataEC50:  50nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM212860(US9278960, 2-7 | US9663506, Example 2-7)
Affinity DataIC50: 54nMAssay Description:Negative allosteric modulation of rat mGluR2 by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50559786(CHEMBL4800093)
Affinity DataEC50:  54nMAssay Description:Positive allosteric modulation of rat mGlu2 receptor expressed in HEK293 cells coexpressing GIRK assessed as thallium influx in presence of EC20 glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393798(US9969726, Example 87 | US10597367, Example 87)
Affinity DataEC50:  60nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393798(US9969726, Example 87 | US10597367, Example 87)
Affinity DataEC50:  60nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393831(US9969726, Example 119 | US10597367, Example 119)
Affinity DataEC50:  60nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393849(US9969726, Example 137 | US10597367, Example 137)
Affinity DataEC50:  60nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393831(US9969726, Example 119 | US10597367, Example 119)
Affinity DataEC50:  60nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393849(US9969726, Example 137 | US10597367, Example 137)
Affinity DataEC50:  60nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50559789(CHEMBL4762369)
Affinity DataEC50:  62nMAssay Description:Positive allosteric modulation of rat mGlu2 receptor expressed in HEK293 cells coexpressing GIRK assessed as thallium influx in presence of EC20 glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50559795(CHEMBL4779278)
Affinity DataEC50:  62nMAssay Description:Positive allosteric modulation of rat mGlu2 receptor expressed in HEK293 cells coexpressing GIRK assessed as thallium influx in presence of EC20 glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50576832(CHEMBL4855540)
Affinity DataEC50:  63nMAssay Description:Positive allosteric modulator activity at rat mGlu2 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM430126(4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)me...)
Affinity DataIC50: 66nMAssay Description:G ±15 HEK293 cells stably expressing rat mGlu2 were plated in black-walled, clear-bottomed, poly-D-lysine coated 384-well plates in 20 L of assay med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50559794(CHEMBL4752318)
Affinity DataEC50:  69nMAssay Description:Positive allosteric modulation of rat mGlu2 receptor expressed in HEK293 cells coexpressing GIRK assessed as thallium influx in presence of EC20 glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393834(US9969726, Example 122 | US10597367, Example 122)
Affinity DataEC50:  70nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393829(US9969726, Example 117 | US10597367, Example 117)
Affinity DataEC50:  70nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM393829(US9969726, Example 117 | US10597367, Example 117)
Affinity DataEC50:  70nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

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