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Report error Found 334 for UniProtKB: P42227
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337196(N2-benzyl-5-((S)-2-((S)-2-(4-cyanobenzamido)-3-(4-...)
Affinity DataKd:  12nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337197(N3-benzyl-5-((S)-2-((S)-2-(4-cyanobenzamido)-3-(4-...)
Affinity DataKd:  17nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337195(GpYLPQTV-NH2 | CHEMBL1684871)
Affinity DataKd:  24nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20242(50, Dihydrocinnamoyl-pTyr-Leu-methanoPro-Gln-NHBn-...)
Affinity DataIC50: 125nMAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20193(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 150nMpH: 7.8 T: 2°CAssay Description:His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3 [127-722](Mouse)
University of Michigan At Ann Arbor

LigandPNGBDBM28130(4-[(2S)-2-{[(3S)-1-({[(1S)-1-(benzylcarbamoyl)-3-c...)
Affinity DataKi:  190nM ΔG°:  -38.0kJ/molepH: 7.5 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337198((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-carbamoyl-[...)
Affinity DataKd:  205nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20211(19, Ac-pTyr-Leu-cis-3,4-methanoPro-Gln-Thr-NH2-2 |...)
Affinity DataIC50: 265nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20200(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 276nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20193(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 290nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3 [127-722](Mouse)
University of Michigan At Ann Arbor

LigandPNGBDBM28128(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-1-(benzylcarbamo...)
Affinity DataKi:  350nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549118(BDBM50556884 | US11299480, Example 53)
Affinity DataIC50: 380nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20266(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 400nMpH: 7.8 T: 2°CAssay Description:His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20253(Y(p)KPQMH | LIFR (1001) derived peptide, 9)
Affinity DataIC50: 400nMpH: 7.8 T: 2°CAssay Description:His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20233(CHEMBL194855 | 4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-1...)
Affinity DataIC50: 409nMAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556886(CHEMBL4753422)
Affinity DataIC50: 460nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549121(BDBM50556885 | US11299480, Example 133)
Affinity DataIC50: 460nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20210(4-[(2S)-2-{[(2S)-1-[(2S,4R)-2-{[(1S)-3-carbamoyl-1...)
Affinity DataIC50: 484nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20198(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 497nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549075(BDBM50556877 | US11299480, Example 34)
Affinity DataIC50: 520nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549137(Sodium (R)-4-(N-(4-cyclohexylbenzyl)-1-((perfluoro...)
Affinity DataIC50: 560nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549077(BDBM50556876 | Sodium (R)-4-(N-(4-cyclohexylbenzyl...)
Affinity DataIC50: 580nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20234(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 596nMAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20195(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 600nMpH: 7.8 T: 2°CAssay Description:His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549103(BDBM50556888 | US11299480, Example 125)
Affinity DataIC50: 630nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556882(CHEMBL4786885)
Affinity DataIC50: 660nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556878(CHEMBL4742343)
Affinity DataIC50: 660nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556887(CHEMBL4799226)
Affinity DataIC50: 700nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556875(CHEMBL4754054 | US11299480, Example 80)
Affinity DataIC50: 710nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20205(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 717nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20195(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 739nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20236((2S)-4-carbamoyl-2-{[(2S)-1-[(2S)-2-[(2S)-2-acetam...)
Affinity DataIC50: 748nMAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20199(4-[(2S)-2-{[(benzyloxy)carbonyl]amino}-2-{[(2S)-1-...)
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556897(CHEMBL4743428)
Affinity DataIC50: 750nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556889(CHEMBL4788858)
Affinity DataIC50: 780nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50335445(2-(2-((4-cyclohexylbenzyl)amino)-6-(4-fluorophenox...)
Affinity DataKd:  800nMAssay Description:Binding affinity to mouse Stat3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20265(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 800nMpH: 7.8 T: 2°CAssay Description:His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50335444(2-(6-(3-bromophenoxy)-2-((4-cyclohexylbenzyl)amino...)
Affinity DataKd:  800nMAssay Description:Binding affinity to mouse Stat3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20235(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 801nMAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549310(BDBM50556881 | US11299480, Example 64)
Affinity DataIC50: 810nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20197(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 814nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20196(CHEMBL194516 | 4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-1...)
Affinity DataIC50: 856nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549083(BDBM50556898 | US11299480, Example 116)
Affinity DataIC50: 860nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20232(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-(m...)
Affinity DataIC50: 882nMAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337199(4-((S)-3-((S)-1-(6-(Benzylcarbamoyl)-4'-carbamoylb...)
Affinity DataKd:  900nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50335408(2-(2-((tert-butoxycarbonyl)(pentyl)amino)-6-(pheny...)
Affinity DataKd:  900nMAssay Description:Binding affinity to mouse Stat3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50556883(CHEMBL4758974)
Affinity DataIC50: 900nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM20204(4-[(2S)-2-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[...)
Affinity DataIC50: 910nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2008
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50335401(2-(2-(4-cyclohexylbenzylamino)-6-phenoxy-9H-purin-...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to mouse Stat3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM549058(US11299480, Example 107 | BDBM50556905)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
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