Compile Data Set for Download or QSAR
Report error Found 684 for UniProtKB: P47746
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176988(8-chloro-1-(2',4'-dichlorophenyl)-N-piperi...)
Affinity DataKi:  0.000350nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176980(8-chloro-1-(2',4'-dichlorophenyl)-N-homopiperidin-...)
Affinity DataKi:  0.00100nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176989(8-chloro-1-(2',4'-dichlorophenyl)-N-pyrrolidin-1-y...)
Affinity DataKi:  0.00400nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176979(8-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.00520nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176986(8-bromo-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-...)
Affinity DataKi:  0.00800nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176990(8-chloro-1-(2',4'-dichlorophenyl)-N-p-methoxylphen...)
Affinity DataKi:  0.0130nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176987(8-methyl-1-(2',4'-dichlorophenyl)-N-pyrrolidin-1-y...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50172545((2-Iodo-phenyl)-[1-(1-methyl-piperidin-2-ylmethyl)...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [131I]-(R)-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176976(8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM239073(US9416103, CP-55,940)
Affinity DataKi:  0.370nM ΔG°:  -53.8kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50088439(CHEMBL3526578)
Affinity DataKi:  0.395nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628520(CHEMBL5430679)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataKi:  0.410nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628548(CHEMBL5420560)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628522(CHEMBL5440946)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM688323(US20240189287, Compound BNS808 | 4-chloro-N-[2-(2-...)
Affinity DataKi:  0.600nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]-CP55,940 from CB1 receptor in mouse whole brain membranes after 60 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628538(CHEMBL5412450)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50256379(methyl 3-(4-chloronaphthalen-1-ylimino)-2-oxa-4-az...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to mouse CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628529(CHEMBL5412938)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628536(CHEMBL5409556)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628540(CHEMBL5436841)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628542(CHEMBL5423328)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataKd:  0.860nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brain at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50060612((5Z,8Z,11Z,14Z)-2,16,16-Trimethyl-docosa-5,8,11,14...)
Affinity DataKi:  1nMAssay Description:Binding affinity for Cannabinoid receptor 1 in presence of phenylmethylsulfonyl fluoride (PMSF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628546(CHEMBL5406438)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM688314(US20240189287, Compound BNS804 | 2-(4-chlorophenox...)
Affinity DataKi:  1.16nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628539(CHEMBL5433824)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50172545((2-Iodo-phenyl)-[1-(1-methyl-piperidin-2-ylmethyl)...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [3H]SR-141,716AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50353747(JWH-018 | CHEMBL561013)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in B6SJL mouse brain membrane after 90 mins by liquid scintillation spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628518(CHEMBL5414090)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM688335(US20240189287, Compound BNS822 | N-[2-(2-chlorophe...)
Affinity DataKi:  1.40nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brain membrane without cerebellum by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP-55940 from CD1 mouse brain CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM688338(US20240189287, Compound BNS825 | N-[2-(2-chlorophe...)
Affinity DataKi:  1.60nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [131I]-(R)-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628535(CHEMBL5434706)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM239078(US9416103, TV-5-157)
Affinity DataKi:  1.70nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM239078(US9416103, TV-5-157)
Affinity DataKi:  1.70nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 1.80nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-CP55,940 from CB1 receptor in CD1 mouse brain membranes after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2018
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628517(CHEMBL5419079)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50364920(CHEMBL1950351)
Affinity DataIC50: 1.90nMAssay Description:Agonist activity at CB1 receptor in field-stimulated mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 2nMAssay Description:Displacement of radioligand from CB1 receptor in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628523(CHEMBL5401334)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50628537(CHEMBL5428613)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]CP55490 from CB1 receptor in mouse brain plasma membrane by radioligand displacement analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM50176981(8-chloro-1-(2',4'-dichlorophenyl)-N-p-chlorophenyl...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Università

Curated by ChEMBL
LigandPNGBDBM463872(US10787419, Serial # 72)
Affinity DataKi:  2.70nMAssay Description:Measuring its tissue levels 1 hour after administration of 10 mg/kg to mice, plasma levels were comparable after oral or i.p. administration (indicat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
US Patent

Displayed 1 to 50 (of 684 total ) | Next | Last >>
Jump to: