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Report error Found 1087 of affinity data for UniProtKB/TrEMBL: P47989
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499668(US11020397, Compound Formula-(IIz))
Affinity DataIC50: 0.0150nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499645(US11020397, Compound Formula-(IIi))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499652(US11020397, Compound Formula-(IIl))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499646(US11020397, Compound Formula-(IIjj))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499675(US11020397, Compound Formula-(IIee))
Affinity DataIC50: 0.0290nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499681(US11020397, Compound Formula-(II5))
Affinity DataIC50: 0.0400nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499657(US11020397, Compound Formula-(IIq))
Affinity DataIC50: 0.0400nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM85771(6-(N-benzoylamino)purine, 2)
Affinity DataKi:  0.0475nM IC50: 450nMAssay Description:Inhibition assay of the xanthine oxidase reaction by various purine based inhibitors was measured in terms of the decrease in uric acid formation at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499684(US11020397, Compound Formula-(II8))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499680(US11020397, Compound Formula-(II4))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499679(US11020397, Compound Formula-(II3))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499673(US11020397, Compound Formula-(IIdd))
Affinity DataIC50: 0.0640nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499683(US11020397, Compound Formula-(II7))
Affinity DataIC50: 0.0700nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50625674(CHEMBL5403463)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50625673(CHEMBL5421553)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499664(US11020397, Compound Formula-(IIv))
Affinity DataIC50: 0.100nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  0.100nMAssay Description:Mixed-type inhibition of xanthine oxidase (unknown origin) assessed as inhibitory constant of enzyme-substrate complex using xanthine as substrate at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  0.100nMAssay Description:Non-competitive inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499670(US11020397, Compound Formula-(IIaa))
Affinity DataIC50: 0.103nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499659(US11020397, Compound Formula-(IIs))
Affinity DataIC50: 0.120nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499662(US11020397, Compound Formula-(IIt))
Affinity DataIC50: 0.180nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499686(US11020397, Compound Formula-(II10))
Affinity DataIC50: 0.190nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499656(US11020397, Compound Formula-(IIp))
Affinity DataIC50: 0.200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499671(US11020397, Compound Formula-(IIbb))
Affinity DataIC50: 0.206nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499658(US11020397, Compound Formula-(IIr))
Affinity DataIC50: 0.210nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499687(US11020397, Compound Formula-(II11))
Affinity DataIC50: 0.220nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499651(US11020397, Compound Formula-(IIk))
Affinity DataIC50: 0.280nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499674(US11020397, Compound Formula-(IIkk))
Affinity DataIC50: 0.315nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499667(US11020397, Compound Formula-(IIy))
Affinity DataIC50: 0.330nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499649(US11020397, Compound Formula-(IIii))
Affinity DataIC50: 0.377nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50449101(CHEMBL3127130)
Affinity DataIC50: 0.501nMAssay Description:Competitive reversible inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499672(US11020397, Compound Formula-(IIcc))
Affinity DataIC50: 0.519nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499685(US11020397, Compound Formula-(II9))
Affinity DataIC50: 0.520nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499678(US11020397, Compound Formula-(II2))
Affinity DataIC50: 0.530nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50449100(CHEMBL3127135)
Affinity DataIC50: 0.631nMAssay Description:Competitive reversible inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499665(US11020397, Compound Formula-(IIw))
Affinity DataIC50: 0.660nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50625624(CHEMBL5436777)
Affinity DataIC50: 1nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50449104(CHEMBL3127117)
Affinity DataIC50: 1nMAssay Description:Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499660(US11020397, Compound Formula-(IIll))
Affinity DataIC50: 1.02nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50625626(CHEMBL5410457)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM499655(US11020397, Compound Formula-(IIo))
Affinity DataIC50: 1.14nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50449108(CHEMBL3127134)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50449106(CHEMBL3127137)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM352052(US9802907, Compound 37)
Affinity DataIC50: 1.32nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50625659(CHEMBL5400293)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to XO (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50449111(CHEMBL3127131)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50449099(CHEMBL3127114)
Affinity DataIC50: 1.60nMAssay Description:Competitive reversible inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
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