Compile Data Set for Download or QSAR
Report error Found 20 of affinity data for UniProtKB/TrEMBL: P48760
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50002471BDBM50002471(CHEMBL289923 | 5-Amino-2-{4-[(2-amino-4-oxo-2,3,4,...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006906BDBM50006906(CHEMBL23977 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-qui...)
Affinity DataKi:  67nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011885BDBM50011885(CHEMBL280864 | 5-Amino-2-{4-[(2,4-diamino-pteridin...)
Affinity DataKi:  150nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50020107BDBM50020107(CHEMBL281656 | 5-Amino-2-{4-[(2,4-diamino-pteridin...)
Affinity DataKi:  300nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006907BDBM50006907(CHEMBL89641 | 2-{4-[(4-Oxo-3,4-dihydro-quinazolin-...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006905BDBM50006905(CHEMBL316019 | 2-{4-[(4-Oxo-3,4-dihydro-benzo[d][1...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005868BDBM50005868(CHEMBL38902 | 2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hex...)
Affinity DataKi:  3.20E+3nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50020102BDBM50020102(CHEMBL28049 | 5-Amino-2-{4-[(2,4-diamino-pteridin-...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005859BDBM50005859(CHEMBL35921 | 5-Amino-2-{4-[(2,4-diamino-pyrido[3,...)
Affinity DataKi:  5.70E+3nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50020101BDBM50020101(CHEMBL281024 | 2-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005867BDBM50005867(CHEMBL40850 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyr...)
Affinity DataKi:  9.00E+3nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367055BDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataKi:  1.76E+4nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50020102BDBM50020102(CHEMBL28049 | 5-Amino-2-{4-[(2,4-diamino-pteridin-...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase obtained from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011886BDBM50011886(CHEMBL36083 | 5-Amino-2-{4-[(2,4-diamino-pteridin-...)
Affinity DataKi:  2.04E+4nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005865BDBM50005865(CHEMBL417696 | 2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-he...)
Affinity DataKi:  2.20E+4nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005860BDBM50005860(CHEMBL41459 | 2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hex...)
Affinity DataKi:  1.15E+5nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18050BDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  1.66E+5nMAssay Description:Compound was tested for its ability to inhibit Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50020099BDBM50020099(CHEMBL283062 | 2-{4-[(2,4-Diamino-pteridin-6-ylmet...)
Affinity DataKi:  3.20E+5nMAssay Description:Inhibitory constant against purified Folyl-polyglutamate synthase from mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005863BDBM50005863(CHEMBL39175 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyr...)
Affinity DataKi:  5.70E+5nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005866BDBM50005866(CHEMBL294973 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-py...)
Affinity DataKi:  2.00E+6nMAssay Description:In vitro inhibition of mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed