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Report error Found 2365 for UniProtKB: P49682
LigandPNGBDBM208709(US9266876, 176)
Affinity DataIC50: 0.100nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208708(US9266876, 175)
Affinity DataIC50: 0.100nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208772(US9266876, 239)
Affinity DataIC50: 0.100nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208707(US9266876, 174)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337251((S)-5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)pipe...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at human CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM208674(US9266876, 141)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208556(US9266876, 23)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337251((S)-5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)pipe...)
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM208720(US9266876, 187)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337250((S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-y...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446659(CHEMBL3116468)
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358617(CHEMBL1921866)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandPNGBDBM208702(US9266876, 169)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358614(CHEMBL1921863)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337250((S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-y...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610449(US10053457, Example 44 | 2-(3-Cyclopropyl-pyrazol-...)
Affinity DataIC50: 0.380nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

LigandPNGBDBM208624(US9266876, 91)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371494(CHEMBL256589)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM208732(US9266876, 199)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358616(CHEMBL1921865)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to IP10 in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446651(CHEMBL3116476)
Affinity DataIC50: 0.400nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610445(US10053457, Example 41 | 2-(3-Cyclopropyl-pyrazol-...)
Affinity DataIC50: 0.450nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

LigandPNGBDBM208627(US9266876, 94)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208706(US9266876, 173)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208629(US9266876, 96)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to MIG in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229439((R)-N-(1-(1-(4-cyanophenyl)-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM228190(1-{(R)-4-[4-(2-Cyclopropyl-pyrimidin-5-yl)-2-trifl...)
Affinity DataIC50: 0.700nMpH: 7.4Assay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229439((R)-N-(1-(1-(4-cyanophenyl)-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610418(US10053457, Example 14 | 2-(5-Fluoro-indol-1-yl)-1...)
Affinity DataIC50: 0.700nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358615(CHEMBL1921864)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229381((R)-N-(1-(3-(4-cyanophenyl)quinolin-2-yl)ethyl)-N-...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]IP-10 from CXCR3 receptor expressed in human PBMC in RPMI-1640 buffer supplemented with 0.5% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to ITAC in RPMI bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446640(CHEMBL3116487)
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM389791(US9951063, 110 | 2-Imidazo[4,5-b]pyridin-3-yl-1-{(...)
Affinity DataIC50: 0.850nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300899((R)-N-(1-(3-(4-cyanophenyl)-8-cyclopropylimidazo[1...)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300907(N-{(R)-1-[3-(4-Cyano-phenyl)-8-cyclopropyl-imidazo...)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358619(CHEMBL1921868)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300905(N-{(R)-1-[3-(4-Cyano-phenyl)-8-cyclopropyl-imidazo...)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358630(CHEMBL1921879)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300900((R)-N-(1-(3-(4-cyanophenyl)-8-methoxyimidazo[1,2-a...)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM228186(2-[3-(1-Hydroxy-ethyl)-[1,2,4]triazol-1-yl]-1-{(R)...)
Affinity DataIC50: 0.900nMpH: 7.4Assay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetC-X-C chemokine receptor type 3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM389773(US9951063, 92)
Affinity DataIC50: 0.970nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent

LigandPNGBDBM208605(US9266876, 72)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208735(US9266876, 202)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

LigandPNGBDBM208617(US9266876, 84)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2017
Entry Details
US Patent

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