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Report error Found 1431 of affinity data for UniProtKB/TrEMBL: P80457
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  0.120nMAssay Description:Mixed-type inhibition of bovine xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to bovine milk xanthine oxidase assessed as reduction in conversion of 4-HPP to 4,6-diHPP by measuring cytochrome c reduction by spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to bovine milk XO using xanthine as substrate assessed as inhibition constant by Dixon plot based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  0.900nMAssay Description:Mixed-type inhibition of bovine xanthine oxidase assessed as enzyme-inhibitor complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50057015(CHEMBL3331617)
Affinity DataKi:  0.900nMAssay Description:Mixed-type inhibition of bovine xanthine oxidase assessed as inhibition of uric acid formation by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625665(CHEMBL5426192)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM352052(US9802907, Compound 37)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625671(CHEMBL5405574)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625672(CHEMBL5395447)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625668(CHEMBL5408526)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM158057(US9023882, 356)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate measured after 10 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM352035(US9802907, Compound 14 | US9802907, Compound 35 | ...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM352045(US9802907, Compound 24)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM158057(US9023882, 356)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625667(CHEMBL5433943)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50497925(CHEBI:70981 | CHEMBL3314206)
Affinity DataKi:  1.80nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625666(CHEMBL5395248)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157887(US9023882, 160)
Affinity DataIC50: 2.10nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM121552(US8729273, 22)
Affinity DataIC50: 2.10nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157874(US9023882, 147)
Affinity DataIC50: 2.10nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157944(US9023882, 233)
Affinity DataIC50: 2.30nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50057015(CHEMBL3331617)
Affinity DataKi:  2.30nMAssay Description:Mixed-type inhibition of bovine xanthine oxidase assessed as inhibition of uric acid formation by secondary Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157880(US9023882, 153)
Affinity DataIC50: 2.40nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM158072(US9023882, 371)
Affinity DataIC50: 2.40nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625670(CHEMBL5405473)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50098066(1-(3-Cyano-4-hydroxy-phenyl)-1H-pyrazole-4-carboxy...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157875(US9023882, 148)
Affinity DataIC50: 2.5nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157886(US9023882, 159)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625669(CHEMBL5406768)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Bovine milk XO measured after 30 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM121532(US8729273, 2)
Affinity DataIC50: 2.80nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM121532(US8729273, 2)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate assessed as decrease in uric acid level measured after 30 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157954(US9023882, 245)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50253763(CHEMBL4067565)
Affinity DataKi:  2.90nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-inhibitor complex using varying levels of xanthine as substrate by Line-weav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataIC50: 3nMAssay Description:Inhibition of bovine xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50127441(CHEMBL3628191)
Affinity DataIC50: 3nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50127486(CHEMBL3628190)
Affinity DataIC50: 3nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50625657(CHEMBL5397172)
Affinity DataIC50: 3nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate measured after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to bovine milk XO using xanthine as substrate assessed as inhibition constant by 1/V-axis intercept replot based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157970(US9023882, 262)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50127486(CHEMBL3628190)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM158054(US9023882, 352)
Affinity DataIC50: 3.20nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50127441(CHEMBL3628191)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157950(US9023882, 240)
Affinity DataIC50: 3.30nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50311264(4-(3-(4-methoxy-3-nitrophenyl)-1H-1,2,4-triazol-5-...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM158056(US9023882, 355)
Affinity DataIC50: 3.30nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM121531(US8729273, 1)
Affinity DataIC50: 3.40nMAssay Description:Xanthine oxidase originated from bovine milk was incubated for 3 min with test compounds, and the initial velocity of uric acid formation was determi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM121531(US8729273, 1)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Bovine milk XO using xanthine as substrate measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-Cyano-4-(2,2-dimethyl-propoxy)-phenyl]-1H-pyr...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase pre-incubated for 3 mins followed xanthine substrate addition and measured every 1 mins for 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM157948(US9023882, 238)
Affinity DataIC50: 3.60nMT: 2°CAssay Description:Xanthine oxidase (from bovine milk, Sigma) was prepared with phosphate-buffered saline (PBS) at 0.02 units/mL, and then the solution was added to 96 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

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