Affinity DataKi: 0.770nMAssay Description:Evaluated for its ability to displace [3H]clonidine from alpha-2 adrenergic receptor of calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Evaluated for its ability to displace [3H]clonidine from alpha-2 adrenergic receptor of calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Compound was evaluated for inhibition of binding of [3H]MK-91 to Alpha-2 adrenergic receptor in bovine pinealMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site A using [3H]clonidineMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]clonidine binding to Alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site A using [3H]clonidineMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site B using [3H]-clonidineMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site B using [3H]-clonidineMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Compound was evaluated for inhibition of binding of [3H]rauwolscine to Alpha-2 adrenergic receptor in bovine pinealMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site B using [3H]-clonidineMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity at Alpha-2 adrenergic receptor in calf cerebral cortex homogenates by [3H]clonidine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Compound was evaluated for log 1/Ki at alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Affinity to alpha-2 adrenergic receptor by the displacement of [3H]clonidine from calf cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro binding affinity towards alpha-adrenoceptor of calf cortex membrane Site A using [3H]clonidineMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro affinity for alpha adrenergic receptor by displacement of 3[H]clonidine in calf cerebral cortexMore data for this Ligand-Target Pair





3D Structure (crystal)



























