Compile Data Set for Download or QSAR
Report error Found 181 for UniProtKB: Q5TZZ4
LigandChemical structure of BindingDB Monomer ID 145285BDBM145285(US8952169, 64 | US9771376, Example 64)
Affinity DataIC50: 11nMAssay Description:Inhibition of human Nav1.1/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530536BDBM50530536(CHEMBL4580996 | US11174268, Example 336)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530536BDBM50530536(CHEMBL4580996 | US11174268, Example 336)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530541BDBM50530541(CHEMBL4468899 | US11174268, Example 38)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530541BDBM50530541(CHEMBL4468899 | US11174268, Example 38)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530533BDBM50530533(CHEMBL4435054 | US11174268, Example 185)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530533BDBM50530533(CHEMBL4435054 | US11174268, Example 185)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530557BDBM50530557(CHEMBL4444000 | US11174268, Example 246)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530557BDBM50530557(CHEMBL4444000 | US11174268, Example 246)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530539BDBM50530539(CHEMBL4460028 | US11174268, Example 300)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530539BDBM50530539(CHEMBL4460028 | US11174268, Example 300)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530537BDBM50530537(CHEMBL4471825)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530547BDBM50530547(CHEMBL4544968 | US11174268, Example 113)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530546BDBM50530546(CHEMBL4530743 | US11174268, Example 52)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530547BDBM50530547(CHEMBL4544968 | US11174268, Example 113)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530537BDBM50530537(CHEMBL4471825)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530546BDBM50530546(CHEMBL4530743 | US11174268, Example 52)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530535BDBM50530535(CHEMBL4466858 | US11174268, Example 205)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530535BDBM50530535(CHEMBL4466858 | US11174268, Example 205)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530538BDBM50530538(CHEMBL4580815)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530538BDBM50530538(CHEMBL4580815)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 145285BDBM145285(US8952169, 64 | US9771376, Example 64)
Affinity DataIC50: 51nMAssay Description:Inhibition of human Nav1.5/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530535BDBM50530535(CHEMBL4466858 | US11174268, Example 205)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530535BDBM50530535(CHEMBL4466858 | US11174268, Example 205)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530539BDBM50530539(CHEMBL4460028 | US11174268, Example 300)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530539BDBM50530539(CHEMBL4460028 | US11174268, Example 300)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530533BDBM50530533(CHEMBL4435054 | US11174268, Example 185)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530533BDBM50530533(CHEMBL4435054 | US11174268, Example 185)
Affinity DataIC50: 66nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530550BDBM50530550(CHEMBL4529272 | US11174268, Example 238)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530550BDBM50530550(CHEMBL4529272 | US11174268, Example 238)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530554BDBM50530554(CHEMBL4457973 | US11174268, Example 59)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530554BDBM50530554(CHEMBL4457973 | US11174268, Example 59)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530553BDBM50530553(CHEMBL4462046)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530553BDBM50530553(CHEMBL4462046)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530534BDBM50530534(CHEMBL4445144 | US11174268, Example 331)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530534BDBM50530534(CHEMBL4445144 | US11174268, Example 331)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530536BDBM50530536(CHEMBL4580996 | US11174268, Example 336)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530536BDBM50530536(CHEMBL4580996 | US11174268, Example 336)
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530542BDBM50530542(CHEMBL4558113 | US11174268, Example 255)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530542BDBM50530542(CHEMBL4558113 | US11174268, Example 255)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530537BDBM50530537(CHEMBL4471825)
Affinity DataIC50: 125nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530537BDBM50530537(CHEMBL4471825)
Affinity DataIC50: 125nMAssay Description:Inhibition of recombinant human full length Nav1.2 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530544BDBM50530544(CHEMBL4474960 | US11174268, Example 76)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530544BDBM50530544(CHEMBL4474960 | US11174268, Example 76)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530558BDBM50530558(CHEMBL4459170 | US11174268, Example 230)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530558BDBM50530558(CHEMBL4459170 | US11174268, Example 230)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 70937BDBM70937(US9694002, 100 | US9546164, 100)
Affinity DataIC50: 202nMAssay Description:Inhibition of human Nav1.1/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530556BDBM50530556(CHEMBL4448084 | US11174268, Example 127)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530556BDBM50530556(CHEMBL4448084 | US11174268, Example 127)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSodium channel protein type 8 subunit alpha/subunit beta-1(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50530559BDBM50530559(CHEMBL4519633 | US11174268, Example 48)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human full length Nav1.6 co-expressed with human SCN1B in HEK293 cells measured after 20 mins at -45 mV holding potential b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 181 total ) | Next | Last >>
Jump to: