Compile Data Set for Download or QSAR
Report error Found 15 of affinity data for UniProtKB/TrEMBL: Q6IE75
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428341BDBM50428341(CHEMBL2331713)
Affinity DataIC50: 1nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012639BDBM50012639(CHEMBL3261053)
Affinity DataIC50: 1nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428340BDBM50428340(CHEMBL2331712)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428342BDBM50428342(CHEMBL2331710)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428343BDBM50428343(CHEMBL2331708)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428340BDBM50428340(CHEMBL2331712)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428343BDBM50428343(CHEMBL2331708)
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428341BDBM50428341(CHEMBL2331713)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012643BDBM50012643(CHEMBL3261062)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428341BDBM50428341(CHEMBL2331713)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428339BDBM50428339(CHEMBL2331714)
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012642BDBM50012642(CHEMBL2403778)
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50428344BDBM50428344(CHEMBL2331711)
Affinity DataIC50: 690nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012641BDBM50012641(CHEMBL3261061)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 2(Rat)
Temple University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012640BDBM50012640(CHEMBL2403779)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of BACE2 in rat INS-1E cells assessed as TMEM27 cleavage preincubated for 2 hrs followed by doxycycline addition measured after 46 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed