Compile Data Set for Download or QSAR
Report error Found 4458 of affinity data for UniProtKB/TrEMBL: Q76353
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50065796(2-[2-(3,4-Dihydroxy-phenyl)-vinyl]-8-hydroxy-quino...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM71542(Primaquine bisphosphate | N4-(6-methoxy-8-quinolin...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM22985(Aralen | Chlorochin | CHLOROQUINE PHOSPHATE | Chlo...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HIV integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HIV1 integrase using labelled oligonucleotide substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50170870(CHEMBL3805182)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50170867(CHEMBL3806067)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273913(CHEMBL4127663)
Affinity DataEC50:  1nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50170867(CHEMBL3806067)
Affinity DataIC50: 1nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50484379(CHEMBL1917873)
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV1 integrase strand transfer by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273950(CHEMBL4128240)
Affinity DataEC50:  1nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of wild type HIV-1 NL4-3 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of HIV-1 NL4-3 integrase T97A/Y143C double mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50183273((S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-met...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50170591(CHEMBL2403116)
Affinity DataIC50: 2nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273951(CHEMBL4126165)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50480704(CHEMBL556894)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity treated after enzyme assembly and washingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50480698(CHEMBL549422)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity treated after enzyme assembly and washingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50489299(CHEMBL2316125)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273952(CHEMBL4130102)
Affinity DataEC50:  2nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273903(CHEMBL4129717)
Affinity DataEC50:  2nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273964(CHEMBL4130252)
Affinity DataEC50:  2nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273965(CHEMBL4127923)
Affinity DataEC50:  2nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273915(CHEMBL4127891)
Affinity DataEC50:  2nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50170870(CHEMBL3805182)
Affinity DataIC50: 2nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in in HIV1 infected human CIP4 cells afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273916(CHEMBL4126289)
Affinity DataEC50:  2nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273914(CHEMBL4126686)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273948(CHEMBL4127873)
Affinity DataEC50:  2nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50183273((S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-met...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV1 integrase by overall integration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50170604(CHEMBL3805585)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM25351(N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of His-tagged HIV-1 integrase-mediated 3' processing and strand transfer reactions using 5'-ACAGGCCTAGCACGCGTCG-Biotin-3' annealed with 5'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using labelled oligonucleotide substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50021581(CHEMBL414850 | L-870810)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50062551(Dolutegravir | GSK1349572 | CHEBI:76010 | S-349572)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50483553(CHEBI:76007 | Dolutegravir Sodium | GSK1349572 | G...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of strand transfer activity of Human immunodeficiency virus 1 Integrase using [3H]labeled target DNA as substrate after 45 mins by scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50483878(CHEMBL1773312)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50045107(GSK364735 | CHEMBL1256978)
Affinity DataIC50: 3nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50480708(CHEMBL550051)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity treated after enzyme assembly and washingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50045083(CHEMBL3310085)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant HIV-1 integrase by strand-transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273902(CHEMBL4126659)
Affinity DataEC50:  3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50042022(CHEMBL3360128)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50480703(CHEMBL559395)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV1 recombinant integrase strand transfer activity treated after enzyme assembly and washingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50492496(Cabotegravir | GSK-1265744A | GSK1265744 | GSK1265...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50489280(CHEMBL2311585)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273916(CHEMBL4126289)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50170865(CHEMBL3805145)
Affinity DataIC50: 3nMAssay Description:Inhibition of pseudotype HIV1 integrase strand transfer activity assessed as reduction in viral replication in HIV1 infected human CIP4 cells after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2017
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50273953(CHEMBL4126840)
Affinity DataEC50:  3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity assessed as reduction in viral replication in presence of 10% fetal bovine serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
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