Compile Data Set for Download or QSAR
Report error Found 50 for UniProtKB: Q7LGC1
LigandChemical structure of BindingDB Monomer ID 411629BDBM411629(US10392391, Compound I-N-58 | US10787452, Compound...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411686BDBM411686(US10392391, Compound I-N-118 | US10787452, Compoun...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411733BDBM411733(US10392391, Compound I-N-166 | US10787452, Compoun...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411749BDBM411749(US10392391, Compound I-N-186 | US10392391, Compoun...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411840BDBM411840(US10392391, Compound I-N-275 | US10787452, Compoun...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411971BDBM411971(US10392391, Compound I-C-25 | US10787452, Compound...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411977BDBM411977(US10392391, Compound I-C-31 | US10787452, Compound...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411989BDBM411989(US10392391, Compound I-C-43 | US10787452, Compound...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412025BDBM412025(US10392391, Compound I-C-79 | US10787452, Compound...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412034BDBM412034(US10392391, Compound I-G-4 | 2-amino-6-fluoro-N-(5...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412037BDBM412037(US10392391, Compound I-G-7 | US10787452, Compound ...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412042BDBM412042(US10392391, Compound I-G-12 | 2-amino-6-fluoro-N-(...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412050BDBM412050(US10392391, Compound I-G-21 | US10787452, Compound...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412060BDBM412060(US10392391, Compound I-G-32 | 2-amino-6-fluoro-N-[...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411573BDBM411573(US10392391, Compound I-N-1 | 2-amino-6-fluoro-N-(4...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411584BDBM411584(US10392391, Compound I-N-13 | US10787452, Compound...)
Affinity DataKi: <20nMAssay Description:Assays were carried out at 25° C. in the presence of 4 nM full-length ATR, 40 nM full-length ATRIP, 40 nM full-length CLK2 and 600 nM TopBP1(A891-S11...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411629BDBM411629(US10392391, Compound I-N-58 | US10787452, Compound...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411686BDBM411686(US10392391, Compound I-N-118 | US10787452, Compoun...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411573BDBM411573(US10392391, Compound I-N-1 | 2-amino-6-fluoro-N-(4...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411584BDBM411584(US10392391, Compound I-N-13 | US10787452, Compound...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411840BDBM411840(US10392391, Compound I-N-275 | US10787452, Compoun...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411971BDBM411971(US10392391, Compound I-C-25 | US10787452, Compound...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411733BDBM411733(US10392391, Compound I-N-166 | US10787452, Compoun...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411749BDBM411749(US10392391, Compound I-N-186 | US10392391, Compoun...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412025BDBM412025(US10392391, Compound I-C-79 | US10787452, Compound...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412034BDBM412034(US10392391, Compound I-G-4 | 2-amino-6-fluoro-N-(5...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411977BDBM411977(US10392391, Compound I-C-31 | US10787452, Compound...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 411989BDBM411989(US10392391, Compound I-C-43 | US10787452, Compound...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412050BDBM412050(US10392391, Compound I-G-21 | US10787452, Compound...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412060BDBM412060(US10392391, Compound I-G-32 | 2-amino-6-fluoro-N-[...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 560106BDBM560106(US11370798, Cmpd. # I-G-7 | US20230271963, Compoun...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 412042BDBM412042(US10392391, Compound I-G-12 | 2-amino-6-fluoro-N-(...)
Affinity DataKi: <200nMAssay Description:Table 7: Compounds were screened for their ability to inhibit ATR kinase, in the presence of partner proteins ATRIP, CLK2 and TopBP1, using a radioac...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083608BDBM50083608(2,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083600BDBM50083600(2,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083599BDBM50083599(1,3,10-trihydroxy-6-(2-hydroxy-1-hydroxymethylethy...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083604BDBM50083604(2,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083611BDBM50083611(3-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083614BDBM50083614(1,3,9,11-tetrahydroxy-6-(2-hydroxy-1-hydroxymethyl...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083613BDBM50083613(1,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083603BDBM50083603(3,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083598BDBM50083598(2-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083607BDBM50083607(1,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083610BDBM50083610(1,9-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylami...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083597BDBM50083597(4-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083606BDBM50083606(1-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083609BDBM50083609(1,10-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083605BDBM50083605(3-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083602BDBM50083602(2-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083601BDBM50083601(1-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-binding protein 1(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076922BDBM50076922(1,11-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro inhibition of Topoisomerase II-mediated DNA cleavage using supercoiled pBR322 plasmid DNA.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed