Compile Data Set for Download or QSAR
Report error Found 391 of affinity data for UniProtKB/TrEMBL: Q80SS6
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156370BDBM50156370(CHEMBL3793436)
Affinity DataEC50:  0.0620nMAssay Description:Agonist activity at mouse TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266580BDBM50266580(CHEMBL4087611)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266544BDBM50266544(CHEMBL4060410)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 398287BDBM398287(US10323016, Example 26)
Affinity DataEC50:  0.5nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003570BDBM50003570(CHEMBL3234869)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003559BDBM50003559(CHEMBL3234570)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614538BDBM50614538(CHEMBL5286836)
Affinity DataEC50:  0.710nMAssay Description:Inhibition of mouse TGR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266538BDBM50266538(US10323016, Example 4 | CHEMBL4084668)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266552BDBM50266552(US10323016, Example 20 | CHEMBL4094487)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019474BDBM50019474(CHEMBL3290717)
Affinity DataEC50:  0.920nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399970BDBM50399970(CHEMBL2181229)
Affinity DataEC50:  0.980nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459101BDBM50459101(CHEMBL4213913)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266538BDBM50266538(US10323016, Example 4 | CHEMBL4084668)
Affinity DataEC50:  1nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003573BDBM50003573(CHEMBL3234871)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266552BDBM50266552(US10323016, Example 20 | CHEMBL4094487)
Affinity DataEC50:  1nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003407BDBM50003407(CHEMBL3234568)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003569BDBM50003569(CHEMBL3234868)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459099BDBM50459099(CHEMBL4202981)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459099BDBM50459099(CHEMBL4202981)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459141BDBM50459141(CHEMBL4212707)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003567BDBM50003567(CHEMBL3234582)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459138BDBM50459138(CHEMBL4209799)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399969BDBM50399969(CHEMBL2181227)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266567BDBM50266567(US10323016, Example 21 | CHEMBL4090147)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459136BDBM50459136(CHEMBL4204655)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459096BDBM50459096(CHEMBL4217797)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003572BDBM50003572(CHEMBL3234870)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459127BDBM50459127(CHEMBL4209669)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003568BDBM50003568(CHEMBL3234583)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003287BDBM50003287(CHEMBL3234577)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266567BDBM50266567(US10323016, Example 21 | CHEMBL4090147)
Affinity DataEC50:  2nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399968BDBM50399968(CHEMBL2181228)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621444BDBM50621444(CHEMBL5394421)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621439BDBM50621439(CHEMBL5437749)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621445BDBM50621445(CHEMBL5422904)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621443BDBM50621443(CHEMBL5415272)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399967BDBM50399967(CHEMBL2181230)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621437BDBM50621437(CHEMBL5427760)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621438BDBM50621438(CHEMBL5414305)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50019475BDBM50019475(CHEMBL3290716)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621440BDBM50621440(CHEMBL5395284)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459140BDBM50459140(CHEMBL4218746)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459145BDBM50459145(CHEMBL4207707)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621442BDBM50621442(CHEMBL5439914)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003336BDBM50003336(CHEMBL3234565)
Affinity DataEC50:  3nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003561BDBM50003561(CHEMBL3234571)
Affinity DataEC50:  3nMAssay Description:Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399962BDBM50399962(CHEMBL2181239)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459124BDBM50459124(CHEMBL4209927)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as increase in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621446BDBM50621446(CHEMBL5398966)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Zydus Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621441BDBM50621441(CHEMBL5413666)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
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