Compile Data Set for Download or QSAR
Report error Found 1369 of affinity data for UniProtKB/TrEMBL: Q8TDU6
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50156370(CHEMBL3793436)
Affinity DataEC50:  0.0570nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399971(CHEMBL2181247)
Affinity DataEC50:  0.230nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50019474(CHEMBL3290717)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50429128(CHEMBL2336232)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399970(CHEMBL2181229)
Affinity DataEC50:  0.310nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50552649(CHEMBL4779837)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50612411(CHEMBL5270816)
Affinity DataEC50:  0.430nMAssay Description:Agonist activity at TGR5 in human HEK293 cells assessed as increase in cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50019475(CHEMBL3290716)
Affinity DataEC50:  0.450nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399969(CHEMBL2181227)
Affinity DataEC50:  0.460nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50612414(CHEMBL5285528)
Affinity DataEC50: <0.5nMAssay Description:Agonist activity at TGR5 in human HEK293 cells assessed as increase in cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399968(CHEMBL2181228)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399967(CHEMBL2181230)
Affinity DataEC50:  0.720nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399966(CHEMBL2181226)
Affinity DataEC50:  0.720nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50565258(CHEMBL4779084)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50612402(CHEMBL5290871)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TGR5 transfected in CHO cells assessed as increase in cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50003559(CHEMBL3234570)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50415407(CHEMBL612138)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50552647(CHEMBL4790044)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50552646(CHEMBL4743463)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50429126(CHEMBL2336233)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50429129(CHEMBL2336231)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50612418(CHEMBL5284434)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells measured after 5.5 hrs by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50019478(CHEMBL3290715)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399962(CHEMBL2181239)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50019479(CHEMBL3290713)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50160886(CHEMBL3794442)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50272009(CHEMBL4126062)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50428105(CHEMBL2331649)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50019485(CHEMBL3290720)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-expressing CRE after 5.5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50429127(CHEMBL2331604)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50003336(CHEMBL3234565)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50428104(CHEMBL2331653)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50565257(CHEMBL4776876)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50019486(CHEMBL3286440)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human TGR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50271998(CHEMBL4127302)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50428101(CHEMBL2331648)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50161836(CHEMBL3793012)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human TGR5 expressed in CHO-K1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50429125(CHEMBL2336234)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at doxycycline-promoter regulated overexpressed human TGR5 receptor in CHO cells assessed as elevation of cAMP level by induced-cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50621437(CHEMBL5427760)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50428095(CHEMBL2331646)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50428102(CHEMBL2331651)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399953(CHEMBL2181240)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50428106(CHEMBL2331655)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 expressed in deoxycycline-induced Flp-In-CHO-TO cells assessed as increase in intracellular cAMP measured after 48 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50565251(CHEMBL4791709)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50621438(CHEMBL5414305)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399962(CHEMBL2181239)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 transfected in HEK293T cells assessed intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50621439(CHEMBL5437749)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50399955(CHEMBL2181256)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50003407(CHEMBL3234568)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
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