Compile Data Set for Download or QSAR
Report error Found 179 of affinity data for UniProtKB/TrEMBL: Q9JJJ7
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205410(CHEMBL3970245)
Affinity DataEC50:  0.0800nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374968(US10251893, Cpd 166)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374968(US10251893, Cpd 166)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205500(CHEMBL3933984)
Affinity DataEC50:  0.130nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205473(CHEMBL3952126)
Affinity DataEC50:  0.140nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205493(CHEMBL3952665)
Affinity DataEC50:  0.180nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374847(US10251893, Cpd 51)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205479(CHEMBL3925918)
Affinity DataEC50:  0.200nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205491(CHEMBL3899701)
Affinity DataEC50:  0.200nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM375004(2-(2'-fluoro-3-methyl-2,4'-bipyridin-5-yl)-N-(5-(p...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM375004(2-(2'-fluoro-3-methyl-2,4'-bipyridin-5-yl)-N-(5-(p...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374847(US10251893, Cpd 51)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205482(CHEMBL3943764)
Affinity DataEC50:  0.260nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428009(CHEMBL2323230)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428001(CHEMBL2322627)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205483(CHEMBL3935037)
Affinity DataEC50:  0.300nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50133870(CHEMBL3188386 | CHEBI:78030 | US10251893, Compound...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205471(CHEMBL3927718)
Affinity DataEC50:  0.400nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205481(CHEMBL3952501)
Affinity DataEC50:  0.400nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374920(US10251893, Cpd 128)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374916(N-(2,3'-bipyridin-6'-yl)-2-(2',3-dimethyl-2,4'-bip...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50133870(CHEMBL3188386 | CHEBI:78030 | US10251893, Compound...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374920(US10251893, Cpd 128)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374916(N-(2,3'-bipyridin-6'-yl)-2-(2',3-dimethyl-2,4'-bip...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205474(CHEMBL3892208)
Affinity DataEC50:  0.430nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428011(CHEMBL2323228)
Affinity DataEC50:  0.450nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205469(CHEMBL3897216)
Affinity DataEC50:  0.480nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50197277(CHEMBL3972086)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428008(CHEMBL2323231)
Affinity DataEC50:  0.5nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374802(US10251893, Cpd 6)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374918(US10251893, Cpd 126)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374802(US10251893, Cpd 6)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374918(US10251893, Cpd 126)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205496(CHEMBL3980962)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205558(CHEMBL3953544)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205498(CHEMBL3981277)
Affinity DataEC50:  0.650nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50205497(CHEMBL3907204)
Affinity DataEC50:  0.700nMAssay Description:Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374948(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374822(2-(4-(2-methylpyridin-4-yl)phenyl)-N-(5-phenylpyri...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374822(2-(4-(2-methylpyridin-4-yl)phenyl)-N-(5-phenylpyri...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374948(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50458259(CHEMBL4215992)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428015(CHEMBL2322632)
Affinity DataEC50:  0.75nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374998(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM374998(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50133870(CHEMBL3188386 | CHEBI:78030 | US10251893, Compound...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50133870(CHEMBL3188386 | CHEBI:78030 | US10251893, Compound...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mouse)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50428006(CHEMBL2323233)
Affinity DataEC50:  1nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Displayed 1 to 50 (of 179 total ) | Next | Last >>
Jump to: