Compile Data Set for Download or QSAR
Report error Found 256 of affinity data for UniProtKB/TrEMBL: Q9UKI7
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 130909BDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human TLK2 using casein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human TLK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human TLK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634884BDBM50634884(CHEMBL5549938)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343559BDBM50343559(1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of TLK2 (unknown origin) in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634876BDBM50634876(CHEMBL5505789)
Affinity DataIC50: 12nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634904BDBM50634904(CHEMBL5505914)
Affinity DataIC50: 15nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634895BDBM50634895(CHEMBL5555013)
Affinity DataIC50: 15nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  16nMAssay Description:Inhibition of TLK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31096BDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  16nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  16nMAssay Description:Binding constant for TLK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  16nMAssay Description:Binding constant for TLK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634906BDBM50634906(CHEMBL5555697)
Affinity DataIC50: 18nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599378BDBM50599378(CHEMBL5204542)
Affinity DataIC50: 19nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634908BDBM50634908(CHEMBL5556475)
Affinity DataIC50: 23nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634848BDBM50634848(CHEMBL5505934)
Affinity DataIC50: 26nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634898BDBM50634898(CHEMBL5556322)
Affinity DataIC50: 27nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599379BDBM50599379(CHEMBL5188455)
Affinity DataIC50: 33nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634872BDBM50634872(CHEMBL5523411)
Affinity DataIC50: 34nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634896BDBM50634896(CHEMBL5512470)
Affinity DataIC50: 36nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634905BDBM50634905(CHEMBL5556177)
Affinity DataIC50: 46nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634900BDBM50634900(CHEMBL5559472)
Affinity DataIC50: 47nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634878BDBM50634878(CHEMBL5518017)
Affinity DataIC50: 48nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506912BDBM50506912(CHEMBL235641)
Affinity DataIC50: 61nMAssay Description:Inhibition of TLK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17032BDBM17032(CHEMBL107225 | (3Z)-2-oxo-3-(1H-pyrrol-2-ylmethyli...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  64nMAssay Description:Binding affinity to TLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  64nMAssay Description:Binding constant for TLK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634885BDBM50634885(CHEMBL5542619)
Affinity DataIC50: 67nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634897BDBM50634897(CHEMBL5558307)
Affinity DataIC50: 77nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634880BDBM50634880(CHEMBL5517951)
Affinity DataIC50: 88nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634877BDBM50634877(CHEMBL5555801)
Affinity DataIC50: 95nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634895BDBM50634895(CHEMBL5555013)
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant human TLK2 (388 to end residues) using myelin basic protein as substrate incubated for 2 hrs in presence of ATP by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634882BDBM50634882(CHEMBL5555855)
Affinity DataIC50: 100nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634856BDBM50634856(CHEMBL5559206)
Affinity DataIC50: 100nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634870BDBM50634870(CHEMBL5555012)
Affinity DataIC50: 100nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634881BDBM50634881(CHEMBL5523653)
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634890BDBM50634890(CHEMBL5555911)
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634873BDBM50634873(CHEMBL5556090)
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634903BDBM50634903(CHEMBL5505767)
Affinity DataIC50: 120nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634874BDBM50634874(CHEMBL5542185)
Affinity DataIC50: 120nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634871BDBM50634871(CHEMBL5558654)
Affinity DataIC50: 130nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634875BDBM50634875(CHEMBL5517792)
Affinity DataIC50: 130nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634887BDBM50634887(CHEMBL5518089)
Affinity DataIC50: 140nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634847BDBM50634847(CHEMBL5505761)
Affinity DataIC50: 140nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634869BDBM50634869(CHEMBL5559521)
Affinity DataIC50: 150nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634928BDBM50634928(CHEMBL5523551)
Affinity DataIC50: 150nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634864BDBM50634864(CHEMBL5523586)
Affinity DataIC50: 160nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599380BDBM50599380(CHEMBL5173181)
Affinity DataIC50: 163nMAssay Description:Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 stai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634865BDBM50634865(CHEMBL5542171)
Affinity DataIC50: 170nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase tousled-like 2(Human)
Center for Lymphoid Malignancies

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634899BDBM50634899(CHEMBL5556812)
Affinity DataIC50: 180nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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