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TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629174(CHEMBL5422959)
Affinity DataIC50: 3nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699325(2-chloro-N-methyl-N-((1-(4- (trifluoromethoxy)phen...)
Affinity DataIC50: 3.5nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630292(US12110276, Compound 49 | CHEMBL5408536)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630290(CHEMBL5438256)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629172(CHEMBL5401444)
Affinity DataIC50: 4nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630292(US12110276, Compound 49 | CHEMBL5408536)
Affinity DataIC50: 4.25nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630291(US12110276, Compound 48 | CHEMBL5411200)
Affinity DataIC50: 4.80nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630291(US12110276, Compound 48 | CHEMBL5411200)
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629173(CHEMBL5415215)
Affinity DataIC50: 7nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629170(CHEMBL5419829)
Affinity DataIC50: 8nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699395(cyclobuten-1-yl-[3-[4- (hydroxymethyl)-1-[4- (trif...)
Affinity DataIC50: 8.70nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699408((E)-3-chloro-1-[3-[4-(hydroxymethyl)- 1-[4- (trifl...)
Affinity DataIC50: 8.80nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630294(US12110276, Compound 112 | CHEMBL5432828)
Affinity DataIC50: 8.90nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630294(US12110276, Compound 112 | CHEMBL5432828)
Affinity DataIC50: 9nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629175(CHEMBL5400400)
Affinity DataIC50: 9nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630293(US12110276, Compound 86 | CHEMBL5403826)
Affinity DataIC50: 9.70nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699469(Cyclobut-1-en-1-yl(3-(1-(4- (trifluoromethoxy)phen...)
Affinity DataIC50: 10nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630293(US12110276, Compound 86 | CHEMBL5403826)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699421(cyclobuten-1-yl-[3-[4-[(1R)-1,2- dihydroxyethyl]-1...)
Affinity DataIC50: 11nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630295(US12110276, Compound 127 | CHEMBL5428867)
Affinity DataIC50: 13nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 0.5 to 4 hrs followed by biotinylated lipid pocket probe addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630295(US12110276, Compound 127 | CHEMBL5428867)
Affinity DataIC50: 13nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699420(1-[3-[4-[(1R)-1,2-dihydroxyethyl]-1- [4- (trifluor...)
Affinity DataIC50: 16nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699421(cyclobuten-1-yl-[3-[4-[(1R)-1,2- dihydroxyethyl]-1...)
Affinity DataIC50: 17nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699416(2-chloro-1-[3-[4-[(1R)-1,2- dihydroxyethyl]-1-[4- ...)
Affinity DataIC50: 17nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699415(2-chloro-1-[3-[4-[(1S)-1,2- dihydroxyethyl]-1-[4- ...)
Affinity DataIC50: 18nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699378(cyclobuten-1-yl-[3-[4-[(1S)-1,2- dihydroxyethyl]-1...)
Affinity DataIC50: 19nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699419(1-[3-[4-[(1S)-1,2-dihydroxyethyl]-1-[4- (trifluoro...)
Affinity DataIC50: 20nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699366(1-[3-[4-[(1R)-1,2-dihydroxyethyl]-1- [4-(pentafluo...)
Affinity DataIC50: 20nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699385(3-[1-[(E)-4-hydroxybut-2- enoyl]azetidin-3-yl]-1-[...)
Affinity DataIC50: 20nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699438((E)-4,4,4-trifluoro-N-[[4- (hydroxymethyl)-1-[4- (...)
Affinity DataIC50: 26nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699348(N-[3-[1-(2-fluoroprop-2- enoyl)azetidin-3-yl]-1-[4...)
Affinity DataIC50: 27nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699311(2-chloro-N-((1-(4- (trifluoromethoxy)phenyl)-1H-in...)
Affinity DataIC50: 29nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699386(3-[1-(2-fluoroprop-2-enoyl)azetidin-3- yl]-1-[4- (...)
Affinity DataIC50: 29nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699343((E)-3-chloro-N-[[4-(hydroxymethyl)-1- [4- (trifluo...)
Affinity DataIC50: 33nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699402((E)-4-hydroxy-1-[3-[4-methyl-1-[4- (trifluorometho...)
Affinity DataIC50: 38nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699327(1-[3-[4-[(1R)-1,2-dihydroxyethyl]-1- [4- (trifluor...)
Affinity DataIC50: 38.5nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699377(1-[3-[4-[(1R)-1,2-dihydroxyethyl]-1- [4- (trifluor...)
Affinity DataIC50: 43nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699400((E)-4-hydroxy-1-[3-[4- (hydroxymethyl)-1-[4- (trif...)
Affinity DataIC50: 48nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699375((E)-4,4-difluoro-N-[[4- (hydroxymethyl)-1-[4- (tri...)
Affinity DataIC50: 51nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699365(1-[3-[4-[(1S)-1,2-dihydroxyethyl]-1-[4- (pentafluo...)
Affinity DataIC50: 52nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699326(2-fluoro-1-[3-[4-(hydroxymethyl)-1-[4- (trifluorom...)
Affinity DataIC50: 58nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699337(1-[3-[4-[(1S)-1,2-dihydroxyethyl]-1-[4- (trifluoro...)
Affinity DataIC50: 62nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699346((E)-1-[3-[4-(hydroxymethyl)-1-[4- (trifluoromethox...)
Affinity DataIC50: 66nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699434(4-hydroxy-N-[[4-(hydroxymethyl)-1- [4- (trifluorom...)
Affinity DataIC50: 72nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699405((Z)-3-chloro-N-[[4-(hydroxymethyl)-1- [4- (trifluo...)
Affinity DataIC50: 87nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM699401((E)-1-[3-[4-[(1R)-1,2-dihydroxyethyl]- 1-[4- (trif...)
Affinity DataIC50: 92nMAssay Description:His-tagged TEAD proteins are pre-incubated with TEAD project compounds for 30 minutes or 4 hours at room temperature. Biotinylated lipid pocket probe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2025
Entry Details
Go to US Patent

TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50629171(CHEMBL5416415)
Affinity DataIC50: 93nMAssay Description:Displacement of biotinylated lipid pocket probes from His-tagged TEAD3 (unknown origin) preincubated for 4 hrs followed by lipid pocket probe additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626290(CHEMBL5430925)
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 30 mins followed by biotinylated lipid pocket addition and measured after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626288(CHEMBL5438096)
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 30 mins followed by biotinylated lipid pocket addition and measured after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50626289(CHEMBL5409535)
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged TEAD3 (unknown origin) preincubated for 30 mins followed by biotinylated lipid pocket addition and measured after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
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