Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 9738
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285658(US10077273, Compound 4 | US10584132, Compound 4 | ...)
Affinity DataIC50:  0.170nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285659(US10077273, Compound 68 | US10584132, Compound 68 ...)
Affinity DataIC50:  0.400nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285663(US10077273, Compound 11 | US10584132, Compound 11 ...)
Affinity DataIC50:  0.400nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285660(US10077273, Compound 1 | US10584132, Compound 1 | ...)
Affinity DataIC50:  0.650nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285660(US10077273, Compound 1 | US10584132, Compound 1 | ...)
Affinity DataIC50:  0.790nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285661(US10077273, Compound 69 | US10584132, Compound 69 ...)
Affinity DataIC50:  0.800nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285662(US10077273, Compound 70 | US10584132, Compound 70 ...)
Affinity DataIC50:  1nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285663(US10077273, Compound 11 | US10584132, Compound 11 ...)
Affinity DataIC50:  1.40nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285659(US10077273, Compound 68 | US10584132, Compound 68 ...)
Affinity DataIC50:  1.70nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285664(US10077273, Compound 71 | US10584132, Compound 71 ...)
Affinity DataIC50:  1.70nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285665(US10077273, Compound 72 | US10584132, Compound 72 ...)
Affinity DataIC50:  2nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285666(US10077273, Compound 2 | US10584132, Compound 2 | ...)
Affinity DataIC50:  2nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285664(US10077273, Compound 71 | US10584132, Compound 71 ...)
Affinity DataIC50:  2.40nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285665(US10077273, Compound 72 | US10584132, Compound 72 ...)
Affinity DataIC50:  4nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285666(US10077273, Compound 2 | US10584132, Compound 2 | ...)
Affinity DataIC50:  4nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM485192(US10934305, Compound HK-16 (PK-2))
Affinity DataIC50:  5nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285688(US10077273, Compound HK-X2 | US10934305, Compound ...)
Affinity DataIC50:  5nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285667(US10077273, Compound 73 | US10584132, Compound 73 ...)
Affinity DataIC50:  7.5nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285689(US10077273, Compound HK-X3 | US10934305, Compound ...)
Affinity DataIC50:  7.80nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285668(US10077273, Compound 8 | US10584132, Compound 8 | ...)
Affinity DataIC50:  8nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285687(US10077273, Compound HK-X1 | US10934305, Compound ...)
Affinity DataIC50:  13nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285688(US10077273, Compound HK-X2 | US10934305, Compound ...)
Affinity DataIC50:  13nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM485192(US10934305, Compound HK-16 (PK-2))
Affinity DataIC50:  15nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285689(US10077273, Compound HK-X3 | US10934305, Compound ...)
Affinity DataIC50:  16.9nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285669(US10077273, Compound 74 | US10584132, Compound 74 ...)
Affinity DataIC50:  17nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285669(US10077273, Compound 74 | US10584132, Compound 74 ...)
Affinity DataIC50:  19nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285685(US10077273, Compound HK-15 | US10934305, Compound ...)
Affinity DataIC50:  20nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285686(US10077273, Compound HK-16 | US10077273, Compound ...)
Affinity DataIC50:  21nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285686(US10077273, Compound HK-16 | US10077273, Compound ...)
Affinity DataIC50:  27nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285685(US10077273, Compound HK-15 | US10934305, Compound ...)
Affinity DataIC50:  35nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285690(6-amino-4-(3-bromo-5-(trifluoromethyl)phenyl)-4-is...)
Affinity DataIC50:  42nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285668(US10077273, Compound 8 | US10584132, Compound 8 | ...)
Affinity DataIC50:  43nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285687(US10077273, Compound HK-X1 | US10934305, Compound ...)
Affinity DataIC50:  66nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285684(US10077273, Compound HK-14 | US10934305, Compound ...)
Affinity DataIC50:  67nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285685(US10077273, Compound HK-15 | US10934305, Compound ...)
Affinity DataIC50:  100nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285684(US10077273, Compound HK-14 | US10934305, Compound ...)
Affinity DataIC50:  131nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285682(US10077273, Compound HK-12 | US10934305, Compound ...)
Affinity DataIC50:  168nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285682(US10077273, Compound HK-12 | US10934305, Compound ...)
Affinity DataIC50:  206nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM485179(US10934305, Compound HK-5 | US10934305, Compound H...)
Affinity DataIC50:  400nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285677(US10077273, Compound HK-7 | US10934305, Compound H...)
Affinity DataIC50:  400nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285683(US10077273, Compound HK-13 | US10934305, Compound ...)
Affinity DataIC50:  500nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285680(US10077273, Compound HK-10 | US10934305, Compound ...)
Affinity DataIC50:  593nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM485179(US10934305, Compound HK-5 | US10934305, Compound H...)
Affinity DataIC50:  756nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285673(US10077273, Compound HK-3 | US10934305, Compound H...)
Affinity DataIC50:  1.19E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285680(US10077273, Compound HK-10 | US10934305, Compound ...)
Affinity DataIC50:  1.19E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM485175(US10934305, Compound HK-1 | US10934305, Compound H...)
Affinity DataIC50:  1.77E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285679(US10077273, Compound HK-9 | US10934305, Compound H...)
Affinity DataIC50:  3.46E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285676(US10077273, Compound HK-6 | US10934305, Compound H...)
Affinity DataIC50:  4.58E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, mitochondrial(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM285672(US10077273, Compound HK-2 | US10934305, Compound H...)
Affinity DataIC50: >5.00E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine hydroxymethyltransferase, cytosolic(Homo sapiens (Human))
The Trustees Of Princeton University

US Patent
LigandPNGBDBM485191(US10934305, Compound HK-16 (PK-1))
Affinity DataIC50: >5.00E+3nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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