BDBM50402289 TENATOPRAZOLE
SMILES COc1ccc2[nH]c(nc2n1)S(=O)Cc1ncc(C)c(OC)c1C
InChI Key InChIKey=ZBFDAUIVDSSISP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50402289
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 2(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IDO2 (unknown origin)More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
TargetCytosolic endo-beta-N-acetylglucosaminidase(Homo sapiens (Human))
University of Utah
Curated by ChEMBL
University of Utah
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat...More data for this Ligand-Target Pair