TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human HSL expressed in Sf9 insect cells using PNPB as substrate measured after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of HSL in rat adipocytes assessed as reduction in lipolysis by measuring glycerol concentration incubated for 30 mins by spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of STAT6 in IL4-stimulated human FW4 reporter cells by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of HSL in rat adipocytes assessed as reduction in lipolysis by measuring glycerol concentration incubated for 30 mins by spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of HSL in rat adipocytes assessed as reduction in lipolysis by measuring glycerol concentration incubated for 30 mins by spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HSL in rat adipocytes assessed as reduction in lipolysis by measuring glycerol concentration incubated for 30 mins by spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
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