BDBM220131 US9278925, V.1-b

SMILES Cc1ccc(cc1C1=C(O)[C@]2(CC[C@@H](CC2)C(F)(F)F)NC1=O)-c1ccc(Cl)cc1

InChI Key InChIKey=AVWHXEGGMYSKIH-MIRVZWSXSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 220131   

TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220131(US9278925, V.1-b)
Affinity DataIC50:  109nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220131(US9278925, V.1-b)
Affinity DataIC50:  940nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2 [27-2458](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220131(US9278925, V.1-b)
Affinity DataIC50:  1.22E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1 [39-2346](Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM220131(US9278925, V.1-b)
Affinity DataIC50:  111nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 nl of a 100-times concentrated solution of the test substance in DMSO were pipetted into a white low-volume 384-well microtitre pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent