BDBM342241 6-(1,3-dimethylpyrazol-4-yl)-4-[4-(4- methyl-5-phenyl-1H-imidazol-2-yl)-1- piperidyl]-7H-pyrrolo[2,3-d]pyrimidine::US9771369, Compound P-3073

SMILES Cc1nn(C)cc1-c1cc2c(N3CCC(c4nc(C)c(-c5ccccc5)[nH]4)CC3)ncnc2[nH]1

InChI Key InChIKey=UEJPFPBZOZOELI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342241   

LigandChemical structure of BindingDB Monomer ID 342241BDBM342241(US9771369, Compound P-3073 | 6-(1,3-dimethylpyrazo...)
Affinity DataKi:  500nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandChemical structure of BindingDB Monomer ID 342241BDBM342241(US9771369, Compound P-3073 | 6-(1,3-dimethylpyrazo...)
Affinity DataKi:  500nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent