BDBM81339 MorphGTP (8b)

SMILES Nc1nc2n([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C3O)c(nc2c(=O)[nH]1)N1CCOCC1

InChI Key InChIKey=YYAPYNUGMUZNGD-YEFCAQKCSA-K

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81339   

TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81339(MorphGTP (8b))
Affinity DataIC50:  1.79E+5nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Aquifex aeolicus)
University Of Amsterdam

LigandPNGBDBM81339(MorphGTP (8b))
Affinity DataIC50:  1.39E+5nM Kd:  714nMpH: 7.5Assay Description:The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed