TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 3.5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 19nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 23nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 29nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 32nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 38nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at recombinant rat P2X1 receptor expressed in Xenopus oocytes assessed as ion flux stimulationMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 51nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 58nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration against human P2X purinoceptor 1 expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 71nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 76nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 77nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 91nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Antagonist activity at mouse P2X1 receptorMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human P2X1R transfected in CHO-K1 cells preincubated for 30 mins followed by alpha,beta-meATP addition by luminescence based a...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 172nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 180nMAssay Description:Antagonist activity at P2X1 receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 199nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 210nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 219nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Gwangju Institute Of Science And Technology (Gist)
Curated by ChEMBL
Affinity DataIC50: 267nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 323nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 335nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair