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Found 30 with Last Name = 'bohl' and Initial = 'ce'
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataKi:  0.270nM ΔG°:  -50.8kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18699((2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trif...)
Affinity DataKi:  0.300nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50215713(2-Chloro-4-((3aS,4R)-4-hydroxy-1,1,3-trioxo-tetrah...)
Affinity DataKi:  0.450nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM26260((2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2...)
Affinity DataKi:  0.540nM ΔG°:  -49.2kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18177(4-[(1S,7S,7aR)-1-ethyl-7-hydroxy-3-oxo-hexahydro-1...)
Affinity DataKi:  0.900nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50258751((R)-2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)-1,1,...)
Affinity DataKi:  1.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM26262((2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromet...)
Affinity DataKi:  1.40nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18522(6-(1-Pyrrolidine)quinolin-2(1H)-one, 6a | 6-[(2R,5...)
Affinity DataKi:  1.5nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18524(6-[bis(2,2,2-trifluoroethyl)amino]-4-(trifluoromet...)
Affinity DataKi:  1.5nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18685((2R)-3-{[4-(2-chloroacetamido)phenyl]sulfanyl}-N-[...)
Affinity DataKi:  1.65nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM26261((2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(tr...)
Affinity DataKi:  1.70nM ΔG°:  -46.5kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM26261((2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(tr...)
Affinity DataKi:  1.70nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18173(4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrro...)
Affinity DataKi:  2.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM26259((2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydro...)
Affinity DataKi:  2.5nM ΔG°:  -45.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18665((2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[...)
Affinity DataKi:  4nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM18665((2S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-[...)
Affinity DataKi:  4nM ΔG°:  -44.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50258791(4-(3-exo-Hydroxy-8-azabicyclo[3.2.1]oct-8-yl)napht...)
Affinity DataKi:  5nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM18663((2S)-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-n...)
Affinity DataKi:  6.10nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18663((2S)-3-(4-fluorophenoxy)-2-hydroxy-2-methyl-N-[4-n...)
Affinity DataKi:  6.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18216((2R)-2-methyl-1-(2,2,2-trifluoroethyl)-9-(trifluor...)
Affinity DataKi:  7.10nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
The Ohio State University

LigandPNGBDBM18678((2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-f...)
Affinity DataKi:  11nM ΔG°:  -42.2kJ/molepH: 7.4 T: 2°CAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki = (IC50 x Kd)/(Kd+[L]) where [L] is the concentration of [3H]MIB (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50258752(2-(4-(dimethylamino)-6-nitro-1,2,3,4-tetrahydroqui...)
Affinity DataKi:  14.9nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50241192((S)-3-methyl-5-trifluoromethyl-3,4-dihydro-2H-pyra...)
Affinity DataKi:  630nMAssay Description:Agonist activity at androgen receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50345228((R)-3-(2-benzylphenylsulfonyl)-N-(4-cyano-3-(trifl...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to wild type androgen receptor by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50345229((R)-3-(biphenyl-2-ylsulfonyl)-N-(4-cyano-3-(triflu...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to wild type androgen receptor by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50345227((R)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydrox...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to wild type androgen receptor by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50345228((R)-3-(2-benzylphenylsulfonyl)-N-(4-cyano-3-(trifl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at wild type androgen receptor expressed in african green monkey CV1 cells assessed as inhibition of dihydrotestosterone-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50345227((R)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydrox...)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at wild type androgen receptor expressed in african green monkey CV1 cells assessed as inhibition of dihydrotestosterone-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM50345229((R)-3-(biphenyl-2-ylsulfonyl)-N-(4-cyano-3-(triflu...)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at wild type androgen receptor expressed in african green monkey CV1 cells assessed as inhibition of dihydrotestosterone-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Gtx

Curated by ChEMBL
LigandPNGBDBM18190(6-ethyl-4-(trifluoromethyl)-1H,2H,6H,7H,8H,9H-pyri...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at androgen receptor (unknown origin) assessed as receptor transactivation by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed