TargetProtein kinase C alpha/beta/gamma/delta/epsilon/eta/theta type/Serine/threonine-protein kinase D1/D3(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Displacement of [3H]PDBu binding to Protein kinase C of CEM cells with 10% fetal calf serumMore data for this Ligand-Target Pair
TargetProtein kinase C alpha/beta/gamma/delta/epsilon/eta/theta type/Serine/threonine-protein kinase D1/D3(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Displacement of [3H]PDBu from Protein kinase C of CEM cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.990nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 h...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Forma Therapeutics
Curated by ChEMBL
Forma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human Myc-DDK-tagged IDH1 R132H mutant expressed in human U87MG cells assessed as reduction in 2-HG levels after 24 hrs by RapidFire hi...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Forma Therapeutics
Curated by ChEMBL
Forma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Myc-DDK-tagged IDH1 R132G mutant expressed in human U87MG cells assessed as reduction in 2-HG levels after 24 hrs by RapidFire hi...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 h...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Forma Therapeutics
Curated by ChEMBL
Forma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human Myc-DDK-tagged IDH1 R132H mutant assessed as reduction in NADPH consumption pre-incubated for 15 mins followed by alpha-ketogluta...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Forma Therapeutics
Curated by ChEMBL
Forma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human Myc-DDK-tagged IDH1 R132C mutant expressed in human U87MG cells assessed as reduction in 2-HG levels after 24 hrs by RapidFire hi...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Forma Therapeutics
Curated by ChEMBL
Forma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of IDH1 R132H mutant in human HCT116 cells assessed as reduction in 2-HG levels after 24 hrs by RapidFire high-throughput mass spectrometr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair