Affinity DataIC50: 2.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 13.7nMAssay Description:Inhibitory activity against Cathepsin B was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 21.6nMAssay Description:Inhibitory activity against Cathepsin B was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 36.6nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 60.9nMAssay Description:Inhibitory activity against Cathepsin B was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 62.9nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 83.3nMAssay Description:Inhibition of human HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 344nMAssay Description:Inhibition of alpha-glucosidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 488nMAssay Description:Inhibition of Clostridium perfringens neuraminidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 531nMAssay Description:Inhibition of alpha-glucosidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibition of bovine cathepsin B after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of bovine cathepsin B after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.03E+3nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 8.82E+3nMAssay Description:Inhibition of alpha-glucosidaseMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PIM1 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of recombinant MMP2More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of truncated recombinant MT1-MMP expressed in Escherichia coli JM109 after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of MMP14 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg- NH2 as substrate preincubated for 10 mins measured after 3 hrs by fluorescence ass...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of truncated recombinant MT1-MMP expressed in Escherichia coli JM109 after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Macquarie University
Curated by ChEMBL
Macquarie University
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-32P] ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair