BDBM50213272 CHEBI:6426::Leupeptin
SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O
InChI Key InChIKey=GDBQQVLCIARPGH-ULQDDVLXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50213272
Affinity DataKi: 5nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Competitive inhibition of recombinant human cathepsin K expressed in Pichia pastoris using Z-FR-MCA as substrate by Dixon plot methodMore data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:Compound was tested for its inhibitory activity against cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of trypsin (unknown origin) using Nalpha-benzoyl-D/L-arginine-4-nitroanilide hydrochloride as substrate preincubated for 5 mins followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 42.2nMAssay Description:Inhibition of human Cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 21.6nMAssay Description:Inhibitory activity against Cathepsin B was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of papaya papain using cbzFRamc substrate preincubated for 10 mins followed by addition of substrate and measured every 30 sec for 60 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against human erythrocyte Calpain 1More data for this Ligand-Target Pair