Found 193 Enz. Inhib. hit(s) with Target = 'Parathyroid hormone/parathyroid hormone-related peptide receptor'
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 83nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 112nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 288nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 562nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 617nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 676nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 708nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 933nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 2.82E+3nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 3.39E+3nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: <1.00E+5nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Displacement of 125I-PTH (1 to 15 residues) from human PTHR1 expressed in African green monkey COS7 cell membranes at 300 uM after 90 mins by gamma c...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 6.87nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 13.5nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 55.4nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cells in presence of SW106More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human PTHR1 expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-induced cAMP ac...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-indu...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-indu...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 98.2nMAssay Description:Displacement of [125I]DPC-AJ1951 from PTH/PTH-related peptide receptor (unknown origin) expressed in HKRK-B28 cellsMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-indu...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human PTHR1 expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-induced cAMP ac...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-indu...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-indu...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Antagonist activity against human PTHR1 expressed in CHO-K1 cells assessed as reduction in PTH induced cAMP level incubated for 30 mins in presence o...More data for this Ligand-Target Pair