Found 4 Enz. Inhib. hit(s) with Target = 'Parathyroid hormone/parathyroid hormone-related peptide receptor' and Ligand = 'BDBM50318885' TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Displacement of 125I-PTH (1 to 15 residues) from human PTHR1 expressed in African green monkey COS7 cell membranes at 300 uM after 90 mins by gamma c...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at human PTHR1 expressed in HKRKB7 cells assessed as accumulation of intracellular cAMP after 20 mins by enzyme immunoassayMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at PTH1R overexpressed in HEK293 cells assessed as intracellular cAMP productionMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
Chugai Pharmaceutical
Curated by ChEMBL
Chugai Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at PTH1R overexpressed in HEK293 cells assessed as intracellular cAMP mobilizationMore data for this Ligand-Target Pair
