Found 8 of ec50 for monomerid = 50058046 TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Chicago Medical Center
Curated by ChEMBL
University Of Chicago Medical Center
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
3D Structure (crystal)TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Organon Research And Development Group
Curated by ChEMBL
Organon Research And Development Group
Curated by ChEMBL
Affinity DataEC50: 4.10E+3nMAssay Description:GABA-modulatory action compound was evaluated on Oocytes expressing recombinant human alpha-1-beta-3-gamma-2L GABA A receptor at concentrations of >=...More data for this Ligand-Target Pair
Target InfoGoogleScholar
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Organon Research And Development Group
Curated by ChEMBL
Organon Research And Development Group
Curated by ChEMBL
Affinity DataEC50: 5.40E+3nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10...More data for this Ligand-Target Pair
Target InfoGoogleScholar
Affinity DataEC50: 8.00E+3nMAssay Description:Modulation of GABA-induced chloride currents in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Chicago Medical Center
Curated by ChEMBL
University Of Chicago Medical Center
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.12E+4nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40E+4nMAssay Description:Direct activation of chloride current in Xenopus laevis oocytes expressing human alpha-1beta1-gamma2 GABA-A receptor subunitsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Organon Research And Development Group
Curated by ChEMBL
Organon Research And Development Group
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:GABA-mimetic action on Oocytes expressing human alpha-1-beta-3-gamma-2L GABA-A receptor subunits at >=100 uMMore data for this Ligand-Target Pair
Target InfoGoogleScholar
