Report error Found 6 Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2' and Ligand = 'BDBM50058046'
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Organon Research and Development Group
Curated by ChEMBL
Organon Research and Development Group
Curated by ChEMBL
Affinity DataEC50: 4.10E+3nMAssay Description:GABA-modulatory action compound was evaluated on Oocytes expressing recombinant human alpha-1-beta-3-gamma-2L GABA A receptor at concentrations of >=...More data for this Ligand-Target Pair
3D Structure (crystal)TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Organon Research and Development Group
Curated by ChEMBL
Organon Research and Development Group
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:GABA-mimetic action on Oocytes expressing human alpha-1-beta-3-gamma-2L GABA-A receptor subunits at >=100 uMMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Organon Research and Development Group
Curated by ChEMBL
Organon Research and Development Group
Curated by ChEMBL
Affinity DataEC50: 5.40E+3nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3gamma2L in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Organon Research and Development Group
Curated by ChEMBL
Organon Research and Development Group
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of [3H]azietomidate labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in ph...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Organon Research and Development Group
Curated by ChEMBL
Organon Research and Development Group
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of [3H]pTFD-di-iPr-BnOH labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Organon Research and Development Group
Curated by ChEMBL
Organon Research and Development Group
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of [3H]R-mTFD-MPAB labelling of GABAA alpha1beta3gamma2L (unknown origin) expressed in Xenopus laevis oocytes assessed as reduction in pho...More data for this Ligand-Target Pair
