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Compile Data Set for Download or QSAR

Found 3 hits of ki data for polymerid = 10603   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acid ceramidase


(Homo sapiens (Human))
BDBM50511298
PNG
(CHEMBL4451058)
Show SMILES CC(C)CNC(=O)n1c2ccc(cc2oc1=O)C1CCN(C)CC1
Show InChI InChI=1S/C18H25N3O3/c1-12(2)11-19-17(22)21-15-5-4-14(10-16(15)24-18(21)23)13-6-8-20(3)9-7-13/h4-5,10,12-13H,6-9,11H2,1-3H3,(H,19,22)
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0.150n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Time-dependent inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate by fluorescence assay


J Med Chem 63: 3634-3664 (2020)


Article DOI: 10.1021/acs.jmedchem.9b02004
More data for this
Ligand-Target Pair
Acid ceramidase


(Homo sapiens (Human))
BDBM367184
PNG
(2-oxo-N-(4-phenylbutyl)-1,3- benzoxazole-3-carboxa...)
Show SMILES O=C(NCCCCc1ccccc1)n1c2ccccc2oc1=O
Show InChI InChI=1S/C18H18N2O3/c21-17(19-13-7-6-10-14-8-2-1-3-9-14)20-15-11-4-5-12-16(15)23-18(20)22/h1-5,8-9,11-12H,6-7,10,13H2,(H,19,21)
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64n/an/an/an/an/an/an/an/a



Argonne National Laboratory

Curated by ChEMBL


Assay Description
Non-competitive inhibition of human acid ceramidase


J Med Chem 62: 987-992 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01723
More data for this
Ligand-Target Pair
Acid ceramidase (AC)


(Homo sapiens (Human))
BDBM29080
PNG
(CHEMBL280065 | N-oleoylethanolamine | Oleamide MEA...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCO
Show InChI InChI=1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
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CHEBI
CHEMBL
KEGG
PC cid
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Patents


Similars

Article
PubMed
5.00E+5n/an/an/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of acid ceramidase (unknown origin)


J Med Chem 56: 3518-30 (2013)


Article DOI: 10.1021/jm301879g
BindingDB Entry DOI: 10.7270/Q27D2WH5
More data for this
Ligand-Target Pair