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Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50012598
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246384(US9446044, 71)
Affinity DataIC50:  0.990nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246384(US9446044, 71)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of GSK3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of GSK3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  11nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  11nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  21nMAssay Description:Inhibition of DYRK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  23nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  32nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  33nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  37nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  59nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  89nMAssay Description:Inhibition of CLK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  93nMAssay Description:Inhibition of DYRK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  143nMAssay Description:Inhibition of GSK3B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  221nMAssay Description:Inhibition of GSK3B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of CLK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 4(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of DYRK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CLK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant at 3 uM by ITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed