Affinity DataIC50: 0.130nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Tested for the inhibition of [125I]-PYY binding to HEK 293 cells stably expressed with human neuropeptide NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.290nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...More data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Displacement of [125I]PYY from mouse NPY-Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Binding affinity of the compound against human Neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in ratMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity tested against Human Neuropeptide Y5 Receptor.More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]-PYY binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of 125 I-PYY binding to human Neuropeptide Y receptor type 5More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibitory concentration of total specific binding of [125I]- -PYY to HEK 293 cells transfected with Human NPY-Y5 cDNA (compound prepared by manual s...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibitory concentration of total specific binding of [125I]- -PYY to HEK 293 cells transfected with the Human NPY-Y5 cDNA (compound prepared by para...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Antagonistic activity against neuropeptide Y receptor type 5 subtype stably expressed in LM(tk-)cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I]PYY from mouse NPY Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMpH: 7.4 T: 2°CAssay Description:cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk cellsMore data for this Ligand-Target Pair