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Found 925 Enz. Inhib. hit(s) with Target = 'Prokineticin receptor 1'
TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM26335(3-[2-({5-[(4-ethylphenyl)methyl]-1-[(4-methoxyphen...)
Affinity DataKi:  22nM ΔG°:  -45.5kJ/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM26336(6-[(2-aminoethyl)amino]-3-[(4-ethylphenyl)methyl]-...)
Affinity DataKi:  440nM ΔG°:  -37.7kJ/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM26337(6-{[2-(4,5-dihydro-1H-imidazol-2-ylamino)ethyl]ami...)
Affinity DataKi:  4.72E+3nM ΔG°:  -31.6kJ/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250533(US10167273, Example 12 | US10544126, Example 12 | ...)
Affinity DataIC50:  4.70E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250535(US10167273, Example 14 | US10544126, Example 14 | ...)
Affinity DataIC50:  470nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250537(US10167273, Example 16 | US10544126, Example 16 | ...)
Affinity DataIC50:  4.60E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250539(US10167273, Example 18 | US10544126, Example 18 | ...)
Affinity DataIC50:  7.00E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250541(US10167273, Example 20 | US10544126, Example 20 | ...)
Affinity DataIC50:  3.60E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250543(US10167273, Example 22 | US10544126, Example 22 | ...)
Affinity DataIC50:  1.18E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250545(US10167273, Example 24 | US10544126, Example 24 | ...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250547(US10167273, Example 26 | US10544126, Example 26 | ...)
Affinity DataIC50:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250549(US10167273, Example 28 | US10544126, Example 28 | ...)
Affinity DataIC50:  320nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250551(US10167273, Example 30 | US10544126, Example 30 | ...)
Affinity DataIC50:  510nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250553(US10167273, Example 32 | US10544126, Example 32 | ...)
Affinity DataIC50:  3.40E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250555(US10167273, Example 34 | US10544126, Example 34 | ...)
Affinity DataIC50:  240nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250557(US10167273, Example 36 | US10544126, Example 36 | ...)
Affinity DataIC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250559(US10167273, Example 38 | US10544126, Example 38 | ...)
Affinity DataIC50:  3.20E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250561(US10167273, Example 40 | US10544126, Example 40 | ...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250563(US10167273, Example 42 | US10544126, Example 42 | ...)
Affinity DataIC50:  5.90E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250565(US10167273, Example 44 | US10544126, Example 44 | ...)
Affinity DataIC50:  5.10E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250567(US10167273, Example 46 | US10544126, Example 46 | ...)
Affinity DataIC50:  1.00E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250569(US10167273, Example 48 | US10544126, Example 48 | ...)
Affinity DataIC50:  3.80E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250571(US10167273, Example 50 | US10544126, Example 50 | ...)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250573(US10167273, Example 52 | US10544126, Example 52 | ...)
Affinity DataIC50:  2.70E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250575(US10167273, Example 54 | US10544126, Example 54 | ...)
Affinity DataIC50:  5.20E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250577(US10167273, Example 56 | US10544126, Example 56 | ...)
Affinity DataIC50:  950nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250579(US10167273, Example 58 | US10544126, Example 58 | ...)
Affinity DataIC50:  2.40E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250581(US10167273, Example 60 | US10544126, Example 60 | ...)
Affinity DataIC50:  900nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250583(US10167273, Example 62 | US10544126, Example 62 | ...)
Affinity DataIC50:  680nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250585(US10167273, Example 64 | US10544126, Example 64 | ...)
Affinity DataIC50:  890nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250587(US10167273, Example 66 | US10544126, Example 66 | ...)
Affinity DataIC50:  1.01E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250589(US10167273, Example 68 | US10544126, Example 68 | ...)
Affinity DataIC50:  2.02E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250591(US10167273, Example 70 | US10544126, Example 70 | ...)
Affinity DataIC50:  8.62E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250593(US10167273, Example 72 | US10544126, Example 72 | ...)
Affinity DataIC50:  440nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250595(US10167273, Example 74 | US10544126, Example 74 | ...)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250597(US10167273, Example 76 | US10544126, Example 76 | ...)
Affinity DataIC50:  3.73E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250599(US10167273, Example 78 | US10544126, Example 78 | ...)
Affinity DataIC50:  70nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250601(US10167273, Example 80 | US10544126, Example 80 | ...)
Affinity DataIC50:  810nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250603(US10167273, Example 82 | US10544126, Example 82 | ...)
Affinity DataIC50:  1.02E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250605(US10167273, Example 84 | US10544126, Example 84 | ...)
Affinity DataIC50:  720nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250607(US10167273, Example 86 | US10544126, Example 86 | ...)
Affinity DataIC50:  4.60E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250609(US10167273, Example 88 | US10544126, Example 88 | ...)
Affinity DataIC50:  200nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250611(US10167273, Example 90 | US10544126, Example 90 | ...)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250613(US10167273, Example 92 | US11512066, Example 92 | ...)
Affinity DataIC50:  1.85E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250615(US10167273, Example 94 | US10544126, Example 94 | ...)
Affinity DataIC50:  1.74E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250617(US10167273, Example 98 | US10544126, Example 96 | ...)
Affinity DataIC50:  80nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250617(US10167273, Example 98 | US10544126, Example 96 | ...)
Affinity DataIC50:  160nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250621(US10167273, Example 100 | US10544126, Example 100 ...)
Affinity DataIC50:  9.42E+3nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250623(US10167273, Example 102 | US10544126, Example 102 ...)
Affinity DataIC50:  470nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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TargetProkineticin receptor 1(Homo sapiens (Human))
University Of Ferrara

LigandPNGBDBM250625(US10167273, Example 104 | US10544126, Example 104 ...)
Affinity DataIC50:  720nMpH: 7.4 T: 2°CAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
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