Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 8619
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408633(US10358451, Compound 18k-2)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408631((1R,2s,3S,5s,7s)-5-(2-(6-fluoro-5H-imidazo[5,1-a]i...)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408616(1s,3r,5R,7S)-3-(1-hydroxy-2-(5H-imidazo[5,1-a]isoi...)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408617((1s,3r,5R,7S)-3-(2-(6-fluoro-5H-imidazo[5,1-a]isoi...)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408630(4-(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-h...)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408629(1-((3r,5r,7r)-adamantan-1-yl)-2-(6-fluoro-5H-imida...)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408626(US10358451, Compound 15d-3)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408630(4-(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-h...)
Affinity DataIC50: <200nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408631((1R,2s,3S,5s,7s)-5-(2-(6-fluoro-5H-imidazo[5,1-a]i...)
Affinity DataIC50: <200nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408617((1s,3r,5R,7S)-3-(2-(6-fluoro-5H-imidazo[5,1-a]isoi...)
Affinity DataIC50: <200nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408616(1s,3r,5R,7S)-3-(1-hydroxy-2-(5H-imidazo[5,1-a]isoi...)
Affinity DataIC50: <200nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408614(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(1-(2-nitro-4...)
Affinity DataIC50: <200nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408614(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(1-(2-nitro-4...)
Affinity DataIC50: <500nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408629(1-((3r,5r,7r)-adamantan-1-yl)-2-(6-fluoro-5H-imida...)
Affinity DataIC50: <500nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408632(US10358451, Compound 18k-1)
Affinity DataIC50: <500nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM347015(US10202388, Compound 13 | US10358451, Compound 10)
Affinity DataIC50: <500nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408618(US10358451, Compound 15d-1)
Affinity DataIC50: >500nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408622(US10358451, Compound 15d-2)
Affinity DataIC50: >500nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408628(US10358451, Compound 15d-4)
Affinity DataIC50: >500nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent