BDBM408617 (1s,3r,5R,7S)-3-(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)adamantan-1-ol::US10358451, Compound 15d

SMILES OC12CC3CC(C1)CC(C3)(C2)C(=O)CC1c2c(cccc2F)-c2cncn12

InChI Key InChIKey=BLTDGNUKYYMPBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408617   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408617((1s,3r,5R,7S)-3-(2-(6-fluoro-5H-imidazo[5,1-a]isoi...)
Affinity DataIC50: <200nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408617((1s,3r,5R,7S)-3-(2-(6-fluoro-5H-imidazo[5,1-a]isoi...)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent