BDBM408617 (1s,3r,5R,7S)-3-(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)adamantan-1-ol::US10358451, Compound 15d
SMILES OC12CC3CC(C1)CC(C3)(C2)C(=O)CC1c2c(cccc2F)-c2cncn12
InChI Key InChIKey=BLTDGNUKYYMPBO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 408617
Affinity DataIC50: <200nMAssay Description:In vitro TDO enzymatic activity was determined in a mixture of 50 mM potassium phosphate buffer, pH 6.5; 200 nM human TDO enzyme, 300 μM L-Trypt...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair