Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50018363
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194815(4-(ethylthio)-6-phenyl-1,3,5-triazin-2-amine | CHE...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194818(4-(3-(6-methoxypyridin-3-yl)phenyl)-6-(methylthio)...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194824(4-(3-(1H-indol-5-yl)phenyl)-6-(methylthio)-1,3,5-t...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194821(2-amino-4-(3-ethoxy-4-hydroxyphenyl)-6-(4-hydroxyp...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194814(2-amino-4-(4-fluorophenyl)-6-phenylnicotinonitrile...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194815(4-(ethylthio)-6-phenyl-1,3,5-triazin-2-amine | CHE...)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194814(2-amino-4-(4-fluorophenyl)-6-phenylnicotinonitrile...)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194817(2-amino-4-(2-chlorophenyl)-6-phenylnicotinonitrile...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194822(2-amino-4-(4-hydroxy-3-methoxyphenyl)-6-(4-hydroxy...)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194825(2-amino-6-cyclopropyl-4-(4-fluorophenyl)nicotinoni...)
Affinity DataKi:  106nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194811(2-amino-6-phenyl-4-p-tolylnicotinonitrile | CHEMBL...)
Affinity DataKi:  118nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194822(2-amino-4-(4-hydroxy-3-methoxyphenyl)-6-(4-hydroxy...)
Affinity DataKi:  151nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194823(2-amino-4-(4-chlorophenyl)-6-phenylnicotinonitrile...)
Affinity DataKi:  192nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194823(2-amino-4-(4-chlorophenyl)-6-phenylnicotinonitrile...)
Affinity DataKi:  201nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194820(2-amino-4-(3,4-dichlorophenyl)-6-(pyridin-3-yl)nic...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194824(4-(3-(1H-indol-5-yl)phenyl)-6-(methylthio)-1,3,5-t...)
Affinity DataKi:  218nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194826(2-amino-4-(4-fluorophenyl)-6,7-dihydro-5H-cyclopen...)
Affinity DataKi:  232nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194817(2-amino-4-(2-chlorophenyl)-6-phenylnicotinonitrile...)
Affinity DataKi:  239nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194821(2-amino-4-(3-ethoxy-4-hydroxyphenyl)-6-(4-hydroxyp...)
Affinity DataKi:  267nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194811(2-amino-6-phenyl-4-p-tolylnicotinonitrile | CHEMBL...)
Affinity DataKi:  274nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194816(CHEMBL221219 | N-(4-fluorobenzyl)-4-phenyl-6-(trif...)
Affinity DataKi:  287nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194813(CHEMBL221220 | N-(4-fluorobenzyl)-4-(thiophen-2-yl...)
Affinity DataKi:  287nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194812(CHEMBL220287 | N-(4-fluorobenzyl)-4-(3-methoxyphen...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194819(2-amino-6-(2-chlorophenyl)-4-(4-chlorophenyl)nicot...)
Affinity DataKi:  403nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194827(CHEMBL374236 | N-(4-fluorobenzyl)-4-(4-chloropheny...)
Affinity DataKi:  454nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194818(4-(3-(6-methoxypyridin-3-yl)phenyl)-6-(methylthio)...)
Affinity DataKi:  840nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194825(2-amino-6-cyclopropyl-4-(4-fluorophenyl)nicotinoni...)
Affinity DataKi:  865nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194819(2-amino-6-(2-chlorophenyl)-4-(4-chlorophenyl)nicot...)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194820(2-amino-4-(3,4-dichlorophenyl)-6-(pyridin-3-yl)nic...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194827(CHEMBL374236 | N-(4-fluorobenzyl)-4-(4-chloropheny...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194812(CHEMBL220287 | N-(4-fluorobenzyl)-4-(3-methoxyphen...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194813(CHEMBL221220 | N-(4-fluorobenzyl)-4-(thiophen-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50194816(CHEMBL221219 | N-(4-fluorobenzyl)-4-phenyl-6-(trif...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed