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Found 14 Enz. Inhib. hit(s) with all data for entry = 50033507
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50309831(10-Phenyl-7-oxa-8,10-diaza-benzo[a]anthracene-9,11...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346538(CHEMBL1797725)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346540(CHEMBL1797726)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346536(CHEMBL1797739)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346537(CHEMBL1797748)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29040(cambinol)
Affinity DataIC50:  4.07E+4nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346536(CHEMBL1797739)
Affinity DataIC50:  4.99E+4nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346537(CHEMBL1797748)
Affinity DataIC50:  5.08E+4nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM29040(cambinol)
Affinity DataIC50:  5.79E+4nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50309830(2-(2-chlorobenzoyl)-1H-benzo[f]chromen-3(2H)-one |...)
Affinity DataIC50:  8.98E+4nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346539(CHEMBL1797737)
Affinity DataIC50:  1.12E+5nMAssay Description:Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50346539(CHEMBL1797737)
Affinity DataIC50:  1.79E+5nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50309831(10-Phenyl-7-oxa-8,10-diaza-benzo[a]anthracene-9,11...)
Affinity DataIC50:  1.91E+5nMAssay Description:Inhibition of human recombinant SIRT2 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed