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Found 32 Enz. Inhib. hit(s) with all data for entry = 50005467
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  268nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492274(CHEMBL2396912)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492273(CHEMBL2396913)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492275(CHEMBL2396910)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492274(CHEMBL2396912)
Affinity DataIC50:  5.92E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492275(CHEMBL2396910)
Affinity DataIC50:  5.97E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492279(CHEMBL1376358)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492276(CHEMBL2396908)
Affinity DataIC50:  7.19E+4nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492273(CHEMBL2396913)
Affinity DataIC50:  8.89E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492279(CHEMBL1376358)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492278(CHEMBL2396904)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492283(CHEMBL1572608)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492280(CHEMBL2396911)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492283(CHEMBL1572608)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492282(CHEMBL2396903)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492272(CHEMBL2396914)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492284(CHEMBL2396906)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492284(CHEMBL2396906)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492285(CHEMBL2396905)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492285(CHEMBL2396905)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492281(CHEMBL2396909)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492282(CHEMBL2396903)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492277(CHEMBL2396907)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492276(CHEMBL2396908)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492281(CHEMBL2396909)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492280(CHEMBL2396911)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM56957(1H-benzimidazol-2-yl(2-pyridyl)amine | MLS00008191...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492278(CHEMBL2396904)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492277(CHEMBL2396907)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM50492272(CHEMBL2396914)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)

Curated by ChEMBL
LigandPNGBDBM56957(1H-benzimidazol-2-yl(2-pyridyl)amine | MLS00008191...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed