BDBM50492279 CHEMBL1376358
SMILES CCCCNc1nc2ccccc2[nH]1
InChI Key InChIKey=OKKUCNXCFWODOE-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50492279
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 5.96E+4nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 5(Mus musculus)
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of mouse TRPC5 expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential by FMP...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 4(Mus musculus)
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 4(Mus musculus)
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced intracellular calciu...More data for this Ligand-Target Pair