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Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM50755
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
>59666±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM50755
Synonyms:
4-(3-Cyano-6-ethoxy-quinolin-2-yl)-[1,4]diazepane-1-carboxylic acid o-tolylamide | 4-(3-cyano-6-ethoxy-2-quinolinyl)-N-(2-methylphenyl)-1,4-diazepane-1-carboxamide | 4-(3-cyano-6-ethoxy-2-quinolyl)-N-(o-tolyl)-1,4-diazepane-1-carboxamide | 4-(3-cyano-6-ethoxy-quinolin-2-yl)-N-(2-methylphenyl)-1,4-diazepane-1-carboxamide | 4-(3-cyano-6-ethoxyquinolin-2-yl)-N-(2-methylphenyl)-1,4-diazepane-1-carboxamide | MLS000074436 | SMR000006841 | cid_647185
Type:
Small organic molecule
Emp. Form.:
C25H27N5O2
Mol. Mass.:
429.5142
SMILES:
CCOc1ccc2nc(N3CCCN(CC3)C(=O)Nc3ccccc3C)c(cc2c1)C#N
Structure:
Search PDB for entries with ligand similarity: