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Target
Adenosine receptor A2a
Ligand
BDBM50368789
Substrate
n/a
Meas. Tech.
ChEMBL_1736169 (CHEMBL4151705)
Ki
0.891251±n/a nM
Citation
 Yang, X; Michiels, TJM; de Jong, C; Soethoudt, M; Dekker, N; Gordon, E; van der Stelt, M; Heitman, LH; van der Es, D; IJzerman, AP An Affinity-Based Probe for the Human Adenosine A J Med Chem 61:7892-7901 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50368789
Synonyms:
CHEMBL4164058
Type:
Small organic molecule
Emp. Form.:
C19H19FN8O4S
Mol. Mass.:
474.469
SMILES:
Nc1nc(NCCCCNC(=O)c2ccc(cc2)S(F)(=O)=O)nc2nc(nn12)-c1ccco1
Structure:
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