TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.617nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 3 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 0.5 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 0.5 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 0.5 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]ZM241385 human A2AR (1 to 316 residues) expressed in Pichia pastoris SMD1168 cell membranes incubated for 0.5 hrsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 148nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 162nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes by competition association assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 167nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 478nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 1.92E+3nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells after 15 mins by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataIC50: 176nMAssay Description:Displacement of [3H]astemizole from human ERG channel expressed in HEK293 cell membrane after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair