Reaction Details Report a problem with these data
Target
6-phosphogluconolactonase
Ligand
BDBM50045357
Substrate
n/a
Meas. Tech.
ChEMBL_1458977 (CHEMBL3369570)
Kd
10000±n/a nM
Citation
 Gibbs, AC Elements and modulation of functional dynamics. J Med Chem 57:7819-37 (2014) [PubMed]  Article 
Target
Name:
6-phosphogluconolactonase
Synonyms:
6-phosphogluconolactonase | 6pgl
Type:
PROTEIN
Mol. Mass.:
28644.57
Organism:
Trypanosoma brucei
Description:
ChEMBL_109481
Residue:
266
Sequence:
MSFKPTISVHATPQELSAAGCRKIVEIIEASGSQQWPLSIALAGGSTPKMTYARLHDEHLNLLREKRALRFFMGDERMVPADSTDSNYNMAREVLLHDIPDDLVFPFDTSAVTPSAEATSADAMRVAEAYGKQLASLLPLKSVGEAGPKVPVFDVVLLGLGSDGHTASIFPGSQAEKETDGKVVVSVGFPSETMKPKVWRVTLSPATIMQARNVIVLATGAEKKWVVDGILADTAHKAPVARFLRGCEGNVSFLLDKEIAENLAKF
  
Inhibitor
Name:
BDBM50045357
Synonyms:
CHEBI:48928 | CHEMBL1230513
Type:
Small organic molecule
Emp. Form.:
C6H13O10P
Mol. Mass.:
276.1352
SMILES:
O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O |r|
Structure:
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