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Target
Delta-type opioid receptor
Ligand
BDBM88484
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>64556±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88484
Synonyms:
1-[5-[3-[3-(butylamino)-6-methyl-2-imidazo[1,2-a]pyridinyl]phenyl]-3-thiophenyl]ethanone;2,2,2-trifluoroacetic acid | 1-[5-[3-[3-(butylamino)-6-methyl-imidazo[1,2-a]pyridin-2-yl]phenyl]-3-thienyl]ethanone;2,2,2-trifluoroacetic acid | 1-[5-[3-[3-(butylamino)-6-methyl-imidazo[1,2-a]pyridin-2-yl]phenyl]thiophen-3-yl]ethanone;2,2,2-tris(fluoranyl)ethanoic acid | 1-[5-[3-[3-(butylamino)-6-methylimidazo[1,2-a]pyridin-2-yl]phenyl]thiophen-3-yl]ethanone;2,2,2-trifluoroacetic acid | MLS001066062 | SMR000814671 | cid_24891816
Type:
Small organic molecule
Emp. Form.:
C24H25N3OS
Mol. Mass.:
403.54
SMILES:
CCCCNc1c(nc2ccc(C)cn12)-c1cccc(c1)-c1cc(cs1)C(C)=O
Structure:
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