Compile Data Set for Download or QSAR
Report error Found 874 of affinity data for UniProtKB/TrEMBL: O08914
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132713(Methyl arachidonoyl fluorophophonate | methyl -ico...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory potency of Fatty-acid amide hydrolase with Mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247048(methyl icosylphosphonofluoridate | CHEMBL462609)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132714((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenesulfonyl f...)
Affinity DataIC50: 0.110nMAssay Description:Inhibitory potency of Fatty-acid amide hydrolase with Mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247052(2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395423(CHEMBL2165084)
Affinity DataKi:  0.160nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395424(CHEMBL2165083)
Affinity DataKi:  0.180nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.200nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50528930(CHEMBL4471658)
Affinity DataKi:  0.230nMAssay Description:Inhibition of FAAH in mouse brain membranes assessed as inhibitory constant using [14C]-AEA as substrate incubated for 15 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataKi:  0.280nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161528(8-Phenyl-1-(5-pyridin-2-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataKi:  0.290nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161520(1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...)
Affinity DataKi:  0.390nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50324698(Ethyl octylfluorophosphonate | CHEMBL1222256)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395421(CHEMBL2165094)
Affinity DataKi:  0.490nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395420(CHEMBL2165070)
Affinity DataKi:  0.5nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161525(1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...)
Affinity DataKi:  0.520nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161511(1-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-heptan-1-o...)
Affinity DataKi:  0.560nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395423(CHEMBL2165084)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395424(CHEMBL2165083)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161513(7-Phenyl-1-(5-pyridin-2-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataKi:  0.830nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161513(7-Phenyl-1-(5-pyridin-2-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataKi:  0.850nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50528930(CHEMBL4471658)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of FAAH in mouse brain membranes using [14C]-AEA as substrate incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161524(7-Phenyl-1-(5-pyridin-3-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataKi:  1nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161514(7-Phenyl-1-(5-pyridin-4-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataKi:  1nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395421(CHEMBL2165094)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395420(CHEMBL2165070)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247008(octane-1-sulfonyl fluoride | CHEMBL499569)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 2nMAssay Description:Inhibitory potency of Fatty-acid amide hydrolase with Mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132716(methyl dodecylphosphonofluoridoate | CHEMBL113263)
Affinity DataIC50: 2nMAssay Description:Inhibitory potency of Fatty-acid amide hydrolase with Mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50100865((Z)-1-(oxazolo[4,5-b]pyridin-2-yl)octadec-9-en-1-o...)
Affinity DataKi:  2.30nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247051(isopropyl 4-nitrophenyl dodecylphosphonate | CHEMB...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132717(Isopropyl dodecylfluorophosphonate | isopropyl dod...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50157120((Z)-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)octad...)
Affinity DataKi:  3nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM23120(CHEMBL177577 | 7-phenyl-1-[5-(pyridin-2-yl)-1,3-ox...)
Affinity DataKi:  4.70nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM23120(CHEMBL177577 | 7-phenyl-1-[5-(pyridin-2-yl)-1,3-ox...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of mouse FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395427(CHEMBL2165073)
Affinity DataKi:  4.80nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50307081(4-Nitrophenyl 4-((5-(2-(Trifluoromethoxy)phenyl)fu...)
Affinity DataIC50: 5nMAssay Description:Inhibition of FAAH in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50307082(4-Nitrophenyl 4-(3-(3-(Trifluoromethyl)phenoxy)ben...)
Affinity DataIC50: 5nMAssay Description:Inhibition of FAAH in mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50528926(CHEMBL4565200)
Affinity DataKi:  6.90nMAssay Description:Inhibition of FAAH in mouse brain membranes assessed as inhibitory constant using [14C]-AEA as substrate incubated for 15 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395442(CHEMBL2165080)
Affinity DataKi:  7nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161519(8-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-octan-1-on...)
Affinity DataKi:  7.5nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50161523(9-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-nonan-1-on...)
Affinity DataKi:  7.80nMAssay Description:Inhibitor affinity towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or FP-Rh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50323040(1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylamin...)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse brain FAAH assessed as conversion of [3H-ethanolamine]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50395444(CHEMBL2165078)
Affinity DataKi:  8nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50450764(CHEMBL4218039)
Affinity DataIC50: 9nMAssay Description:Inhibition of CD1 mouse FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50426684(CHEMBL2326494)
Affinity DataKi:  10nMAssay Description:Inhibition of FAAH in mouse brain homogenate using [3Hethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50052783(CHEMBL3318605)
Affinity DataIC50: 10nMAssay Description:Inhibition of FP-rhodamine probe binding to FAAH in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
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