Compile Data Set for Download or QSAR
Report error Found 12987 of affinity data for UniProtKB/TrEMBL: P0DTD1
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50642734(CHEMBL5575722)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of SARS-CoV-2 3CL protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM513874(bioRxiv20220126.477782, Screening Hit 2 | bioRxiv2...)
Affinity DataIC50: 0.0130nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50643614(CHEMBL5563071)
Affinity DataKi:  0.0250nMAssay Description:Inhibition of N-terminal hexa-histidine tagged SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using HiLyte Fluor 488TM-ESATLQSGLRK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM510018(WO2021205290, Example 27 | (3S)-3-({N-[(4-methoxy-...)
Affinity DataIC50: 0.0300nMAssay Description:Proteolytic activity of SARS-CoV-2 Coronavirus 3CL protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS-CoV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
WIPO WO2021205290

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM617076(US11753373, Compound D-3-a)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of N-terminal hexa-histidine tagged SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using HiLyte Fluor 488TM-ESATLQSGLRK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50643616(CHEMBL5569828)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of N-terminal hexa-histidine tagged SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using HiLyte Fluor 488TM-ESATLQSGLRK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50643619(CHEMBL5569267)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of N-terminal hexa-histidine tagged SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using HiLyte Fluor 488TM-ESATLQSGLRK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of SARS-CoV-2 MPro assessed as inhibition constant by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50645474(CHEMBL5592467)
Affinity DataKi:  0.170nMAssay Description:Inhibition of SARS-Cov-2 MPro assessed as inhibition constant by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50643610(CHEMBL5589941)
Affinity DataKi:  0.200nMAssay Description:Inhibition of N-terminal hexa-histidine tagged SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using HiLyte Fluor 488TM-ESATLQSGLRK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50614003(CHEMBL5283942)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM581847(WO2022208262, Example 16)
Affinity DataKi:  0.210nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022208262

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50627037(CHEMBL3559293)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21(DE3) cells using DABCYL-KTSAVLQSGFRKM-EDANS as substrate preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50627041(CHEMBL5409350)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21(DE3) cells using DABCYL-KTSAVLQSGFRKM-EDANS as substrate preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataKi:  0.260nMAssay Description:Inhibition of N-terminal hexa-histidine tagged SARS-CoV-2 main protease expressed in Escherichia coli BL21 (DE3) using HiLyte Fluor 488TM-ESATLQSGLRK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli using Dabcyl-KTSAVLQSGFRKME-Edans as substrate incubated for 60 mins by FRET bas...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataKi:  0.270nMAssay Description:The respective human coronavirus Mpro in assay buffer (20 mM Tris-HCl, pH 7.3, 100 mM NaCl, 1 mM EDTA, 5 mM TCEP) and 0.1% BSA was added to assay-rea...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
11/5/2021
Entry Details

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity to SARS-CoV-2 MPro assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity to SARS-CoV-2 MPro assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataKi:  0.270nMAssay Description:PF-00835231 was evaluated against 3CLpro from a variety of other coronaviruses representing alpha, beta and gamma groups of Coronaviridae, using bioc...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
9/21/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM512404(acs.jmedchem.1c00409_ST.1)
Affinity DataIC50: 0.270nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM448299(MI-14)
Affinity DataEC50:  0.300nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM420298(WO2005113580-Ex-02 | PF-00835231 | PF-0835231 | cm...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of SARS-CoV-2 3CLpro using ESATLQSGLRKAK-NH2 as substrate incubated for 10 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50405500(CHEMBL5290840)
Affinity DataIC50: 0.345nMAssay Description:Inhibition of SARS-CoV-2 MPro using Dabcyl-KTSAVLQSGFRKME-Edans as substrate preincubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM728399(US20250092056, Compound I-257)
Affinity DataIC50: 0.350nMAssay Description:In this test, an assay buffer consisting of 20 mM Tris-HCl, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is used. The sample to be tested is diluted in advanc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50589777(CHEMBL5192350)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM728381(US20250092056, Compound I-077)
Affinity DataIC50: 0.360nMAssay Description:In this test, an assay buffer consisting of 20 mM Tris-HCl, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is used. The sample to be tested is diluted in advanc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50589769(CHEMBL5174111)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM728387(US20250092056, Compound I-182)
Affinity DataIC50: 0.400nMAssay Description:In this test, an assay buffer consisting of 20 mM Tris-HCl, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is used. The sample to be tested is diluted in advanc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM448317(MI-31)
Affinity DataEC50:  0.400nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM50589778(CHEMBL5204987)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as fluorescent substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674736(US20240158368, Compound 83)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674693(US20240158368, Compound 40)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674708(US20240158368, Compound 55)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674681(US20240158368, Compound 28)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674710(US20240158368, Compound 57)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674732(US20240158368, Compound 79)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674724(US20240158368, Compound 71)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674683(US20240158368, Compound 30)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674698(US20240158368, Compound 45)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674704(US20240158368, Compound 51)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674711(US20240158368, Compound 58)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674718(US20240158368, Compound 65)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674692(US20240158368, Compound 39)
Affinity DataEC50:  0.420nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM728392(US20250092056, Compound I-230)
Affinity DataIC50: 0.420nMAssay Description:In this test, an assay buffer consisting of 20 mM Tris-HCl, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is used. The sample to be tested is diluted in advanc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674702(US20240158368, Compound 49)
Affinity DataEC50:  0.430nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674661(US20240158368, Compound 8)
Affinity DataEC50:  0.430nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674705(US20240158368, Compound 52)
Affinity DataEC50:  0.430nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674660(US20240158368, Compound 7)
Affinity DataEC50:  0.430nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Ri.MED Foundation

Curated by ChEMBL
LigandPNGBDBM674701(US20240158368, Compound 48)
Affinity DataEC50:  0.430nMAssay Description:SARS-CoV-2 Mpro biochemical assays were performed in 8 μL in 384-well Proxi-Plus plate (PerkinElmer, Waltham, MA USA) at ambient temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent

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